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Electronic Resource

Cell-Specific Gene Expression in Plants (1990)

Edwards, J W ; Coruzzi, G M

Palo Alto, Calif. : Annual Reviews

Annual Review of Genetics 24 (1990), S. 275-303

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ISSN: 0066-4197

Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff

Topics: Biology

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1146/annurev.ge.24.120190.001423

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Effect of occupational exposure to aldrin on urinary d-glucaric acid, plasma dieldrin, and lymphocyte sister chromatid exchange (1994)

Edwards, J. W. ; Priestly, B. G.

Springer

International archives of occupational and environmental health 66 (1994), S. 229-234

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ISSN: 1432-1246

Keywords: Aldrin ; Pesticide ; SCE ; d-Glucaric acid ; Biomonitoring

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The effects of exposure to the chlorinated cyclodiene termiticide aldrin was evaluated in pest control workers potentially exposed to this material. Sister chromatid exchange (SCE) frequencies were not elevated in workers handling aldrin. This is consistent with the fact that chlorinated cyclodienes are not genotoxic. Plasma dieldrin concentrations (up to 250 ng/ml) confirmed exposure in workers actively performing termiticide treatments and in maintenance and store workers, when compared with unexposed control workers (median concentration, 4.8 ng/ml). Urinary d-glucaric acid (DGA), an index of hepatic enzyme activity, was elevated in pesticide-exposed groups but urinary DGA was poorly correlated with plasma dieldrin level. This indicates that concurrent exposures of these groups to other pesticides may have influenced mixed-function oxidase metabolic activity.