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  • 1
    ISSN: 1432-0584
    Keywords: Pure red cell aplasia ; IL-2 ; Cyclosporin A
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We investigated spontaneous cytokine production in two patients with pure red cell aplasia (PRCA). The peripheral blood mononuclear cells (PBMNC) from two patients produced IL-2. Cyclosporin A (CyA) suppressed in vitro IL-2 production in one patient, but not in the other. Spontaneous IL-2 production disappeared in one patient 10 months after the start of CyA therapy. The patient for whom CyA therapy was stopped after the disappearance of spontaneous IL-2 production has remained in continuous remission for 1 year. The present case suggests that spontaneous IL-2 production in PBMNC might be an indicator of disease activity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 251 (1994), S. 113-116 
    ISSN: 1434-4726
    Keywords: Acute otitis media ; Middle ear effusion Children ; Tympanometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using tympanometry we investigated potential changes in both middle ears developing during and after unilateral acute otitis media (AOM) in Japanese children. In 144 children with unilateral AOM, tympanometry was performed at presentation and was repeated at the 1st, 2nd, 3rd, and 4th weeks and then every 2 weeks up to 12 weeks after entry into the study. Type B tympanograms were recorded in 81 (56%) of the affected ears and in 37 (26%) of the unaffected ears at presentation. Twelve weeks after AOM, the type B tympanogram was still observed in 21 (15%) of the affected ears and in 16 (11%) of the unaffected ears. Ears with type B changes at presentation showed a significantly slower recovery of middle ear ventilation than did those with either type A or type C1.
    Type of Medium: Electronic Resource
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