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  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Biologie in unserer Zeit 24 (1994), S. 16-16 
    ISSN: 0045-205X
    Keywords: Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Sexual plant reproduction 3 (1990), S. 1-6 
    ISSN: 1432-2145
    Keywords: Cell-wall lysins ; Chlamydomonas ; Serine proteases ; Volvox
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A cell-wall degrading enzyme has been isolated from mature sperm packets of the green flagellate Volvox carteri (Poona strain). This sperm lysin (S-lysin) is a Ca2+-dependent protease of 34 kDa with an essential serine group in its active centre. Neither SH group-blocking reagents nor transition metal chelators inhibit its action. S-lysin degrades the hydroxyproline-rich glycoprotein structures of the cell walls of sheath cells and gonidia (eggs) of vegetative and sexual spheroids in a characteristic manner. In asexual spheroids the somatic envelope is totally disintegrated, whereas in sexual spheroids pores are formed by local lysis at sites of adjacent eggs. Although S-lysin is very similar to the G-lysin of the closely related Chlamydomonads, it is species specific and does not attack the mother or daughter cell walls of Chlamydomonas reinhardtii. S-lysin resembles the aerosin of animal sperm cells in some aspects of its action.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Sexual plant reproduction 5 (1992), S. 8-12 
    ISSN: 1432-2145
    Keywords: Glycoprotein ; Sexual inducer ; Volvox carteri
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Sexual inducer pheromones fromVolvox carten f.weismannia, strains 65–30(12) and 1B were purified and characterized as glycoproteins with apparent molecular weights of 27 kDa and 28.5 kDa, respectively. This subspecies yielded 20–40 times more pheromone based on weight per spheroid thanVolvox carteri f.nagariensis, but its specific activity (threshold dilution) is four to five orders of magnitude less (10−12 to 10−13 M). Gaschromatographic sugar analysis revealed quantitative differences in the composition of theO- andN-glucans compared with theV. carteri f.nagariensis inducer. TheV. carteri f.weismannia pheromones showed antigenic cross-reaction with an antiserum directed against chemically deglycosylated inducer fromV. carteri f.nagariensis. However, there is only unilateral biological cross-induction. TheV. carteri f.nagariensis inducer is strictly competent for its own gonidia only; the inducers fromV. carteri f.weismannia also cross-induceV. carteri f.nagariensis. This pattern of cross-induction suggests the existence of related pheromone receptors but with different ligand specificities.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 65 (1991), S. 20-26 
    ISSN: 1432-0738
    Keywords: Metallothionein ; DNA strand breaks ; Radicals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The in vitro DNA strand breaking activity of metallothionein (MT) containing Cd2+ and Zn2+ in a molar ratio of 5∶2 is described. Studies with radical scavengers and electron paramagnetic resonance spectroscopy indicate that the DNA damage might be caused by a radical species formed by the native protein (i.e., MT) charged with the heavy metal ions. No DNA strand breaks are detectable with the heat-denatured MT or with Cd2+ or Zn2+ alone. Inhibition studies using EDTA as a metal ion chelator orN-ethylmaleimide to alkylate sulfhydryl groups suggest that both the bound heavy metal ions as well as the SH groups of the various cysteine residues of MT may be involved in the MT-dependent DNA cleavage. Further characterization showed that the DNA cleavage is more likely random than sequence- or base-specific. These observations may provide a clue in the search for initial events in Cd-related carcinogenicity.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The novel iridal 10 has been isolated from rhizome extracts of Iris foetidissima. Its structure was established by spectroscopic methods and oxidative degradation. Final proof of the spirobicyclic nature of the compound - a new feature in the triterpenoid field - was afforded by the correlations observed in the 2D-HMBC- (1H-detected multiple-bond heteronuclear multiple-quantum coherence) spectrum. The possible biogenesis of this unusual compound is discussed.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 25 (1991), S. 8-26 
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 28 (1994), S. 131-133 
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 28 (1994), S. 293-297 
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Mit George A. Olah hat die Königlich Schwedische Akademie der Wissenschaften erstmals und für manche überraschend einen Forscher für Arbeiten auf dem Gebiet organischer Reaktionsmechanismen und reaktiver Zwischenstufen mit dem Nobelpreis ausgezeichnet, eine Ehre, die selbst C. K. Ingold (1893 - 1970), dem Begründer dieser Arbeitsrichtung, versagt blieb. Der Nobelpreis für Medizin und Physiologie ging in diesem Jahr an die beiden US-Amerikaner Alfred G. Gilman und Martin Rodbell für ihre Arbeiten über die G-Proteine.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 25 (1991), S. 29-43 
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Glykoproteine sind, wie der Name sagt, mit Kohlenhydraten mehr order weniger stark kovalent modifizierte Proteine, wobei der Kohlenhydratanteil zwischen einem und 80 Prozent liegt. Glykoproteine kommen in allen Lebewesen (Pro- und Eukaryonten) vor und haben die unterschiedlichsten Funktionen, die vielfach auf spezifische Wechselwirkungen zwischen den zuckerhaltigen Molekülanteilen zurückzuführen sind. Pflanzliche Glykoproteine sind erst in jüngerer Zeit „interessant„ geworden, als man erkannte, daß sie für viele agronomische Vorkommnisse verantwortlich sind, zum Beispiel für die Bindung und Einbindung von Symbionten bei der Knöllchenbildung der Leguminosen, bei der Infektion von Pflanzen mit Viren und Pilzen, bei den Vorgängen der Bestäubung, Befruchtung und Selbststerilität. In der Tat haben Pflanzen eine Art Immunsystem auf diesen Prinzipien entwickelt, das bereit steht, die ökologischen Wechselbeziehungen zu stabilisieren oder zu verteidigen, und damit für die ökonomischen Wechselbeziehungen zwischen Mensch und Primärnahrung wesentlich ist.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 26 (1992), S. 187-195 
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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