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  • 1990-1994  (2)
  • 1
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: A cDNA from a rat hippocampal cDNA library encodes an isoform of the α polypeptide of the γ-aminobutyric acid (GABA)/benzodiazepine (BZ) receptor. Its deduced amino acid sequence is 96% identical to that of the α2 polypeptide of the bovine GABAA receptor. The polypeptide has features shared by all previously reported GABAA receptor α polypeptides and shares 71–76% identity with previously described rat α polypeptides. Most of the differences lie in the presumed extracellular and intracellular domains. On Northern blots, the α2 cDNA detects two mRNAs, which are found in cortex, hippocampus, and striatum, brain regions enriched in pharmacologically defined “BZ type II” receptors. Other workers have previously shown that the α polypeptides of the GABAA receptor largely determine the BZ binding properties of reconstituted receptors. The distribution of α2 mRNAs in rat brain suggests that the α2 subunit may indeed be involved in the BZ type II receptors.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 14 (1992), S. 0 
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A technique was developed to evaluate the relative slip of ten test talcs and two control talcs (one with known good slip and one with known poor slip properties). The study was conducted under double-blind conditions with a naive panel of 19 subjects, who with minimal training ranked the 12 talcs. The rankings identified were in line with expectations. Such sensory analysis could be applied in this cost-effective manner to the evaluation and comparison of many properties of cosmetics and toiletries.
    Type of Medium: Electronic Resource
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