ISSN:
1434-4726
Keywords:
Progressive sensorineural hearing loss
;
Immune diseases
;
Antigen non-specific tests
;
Interleukin-2 receptor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The purpose of the present study was to determine the validity of antigen non-specific immunological tests in order to develop a risk-clinical profile of patients with immune-mediated inner ear pathology. The study was carried out on 38 patients with progressive sensorineural hearing loss and a control group of 26 subjects. Serological testing was used to determine cell activation complexes. In patients with hearing loss, T -lymphocyte subpopulations were found to have an increase in cytotoxic T-cells when compared to T-helper, but only for interleukin-2 receptor expression. This difference was significant between patients and the control group. Present findings suggest that T-lymphocyte “early” marker is of particular interest for developing a risk-clinical profile of patients with sensorineural progressive hearing loss of immune origin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00181884
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