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  • 1985-1989
  • 1980-1984  (2)
  • Smooth pursuit  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Specific oculomotor deficits after amylobarbitone (1983)
    Springer
    Psychopharmacology 79 (1983), S. 187-189 
    Details
    ISSN: 1432-2072
    Keywords: Amylobarbitone ; Barbiturates ; Saccades ; Smooth pursuit ; Psychomotor response ; Humans ; Drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Five healthy volunteers received a single oral dose of amylobarbitone sodium (200 mg) and placebo in a double blind randomized fashion. Peak velocity of horizontal saccadic eye movements, saccade duration and smooth pursuit velocity were measured at intervals up to 6 h after drug administration. The active treatment produced a statistically significant decrease of both saccadic and smooth pursuit eye velocity. The maximum effect was observed 2 h after drug administration. The effect on peak saccadic velocity was still statistically significant 6 h after treatment. The maximum impairment in eye movement performance ranged between 25 and 29%. These results demonstrate that both saccadic and smooth pursuit systems are unable to generate the required eye velocity under the influence of a therapeutic dose of amylobarbitone sodium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427809
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effect of amphetamine on saccadic and smooth pursuit eye movements (1983)
    Springer
    Psychopharmacology 79 (1983), S. 190-192 
    Details
    ISSN: 1432-2072
    Keywords: Amphetamine ; Saccades ; Smooth pursuit ; Psychomotor response ; Humans ; Drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Healthy volunteers received single oral or intravenous doses of d-amphetamine sulphate (15 mg) and placebo in a double blind randomized design. Peak velocity of horizontal saccadic eye movements, saccade duration, saccade reaction time and smooth pursuit velocity were measured at intervals up to 1 h (IV) and 6 h (oral) after drug administration. Amphetamine produced no significant effect on saccadic and smooth-pursuit eye movements after oral administration. However, intravenous amphetamine abolished the effect of fatigue on saccadic movements and significantly (P〈0.01) shortened saccadic reaction time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427810
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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