Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Proteins of the periodontium (1977)
    Springer
    Calcified tissue international 23 (1977), S. 39-44 
    Details
    ISSN: 1432-0827
    Keywords: Dental cementum ; Collagen ; Protein ; Chemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Cyanogen bromide (CNBr) peptides were prepared of the insoluble collagen of bovine dental cementum. Following chromatographic separation, the peptides were identified by their amino-acid composition. Type I collagen ([α1(I)]2α2) accounted for more than 90% of the organic matrix, while Type III collagen ([α1(III)]3) was present at a level of approximately 5%. Amino-acid analyses revealed that the CNBr peptides from α1(I) and α2 chains of cementum closely resembled the corresponding peptides from calf skin. The only systematic difference was a higher level of hydroxylation of prolyl and lysyl residues of the cementum peptides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02012764
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Thermal perturbation techniques in characterizing ligand-macromolecule interactions: Theory and application to the proflavin-α-chymotryspin system (1978)
    New York : Wiley-Blackwell
    Biopolymers 17 (1978), S. 1773-1792 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A thermal perturbation curve (TPC) is defined to be the derivative of the fractional degree of saturation, f, with respect to temperature, considered as a function of the natural logarithm of free ligand concentration, y. The theoretical framework for the use of such curves in the thermodynamic analysis of ligand binding to macromolecules is presented. The thermal perturbation curve either provides or complements the information obtained from the derivative binding isotherm ∂f/∂y. For a single set of identical and independent sites the TPC is identical to the derivative binding isotherm. Analysis of such a curve directly yield ΔH0 and ΔG0 for the binding reaction. In actual experimental work, however, the TPC can only be approximated because of “self-buffering” effects relations between the parameter of the approximate curve and the thermodynamic quantities have been developed. This technique is applied to the proflavin-α-chymotryspin system to demonstrate its usefulness. The general features of thermal perturbation curves for cases of multiple sets of independent sites and cooperatively interacting sites have also been developed. The analysis of thermal perturbation curves in combination with other methods should provide a more powerful approach to the characterization of ligand-macromolecule interactions.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.1978.360170712
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Thermodynamics of mucopolysaccharide-dye binding. I. Identification of free and bound dye via membrane filtration: Acridine orange-dermatan sulfate system (1977)
    New York : Wiley-Blackwell
    Biopolymers 16 (1977), S. 685-693 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Stoichiometric mixtures of acridine orange with dermatan sulfate at total dye concentrations ≤ 1 × 10-5 M show fluorescence maxima at 540 nm and 660 nm on excitation at 436 nm. By means of membrane filtration, it is directly demonstrated that the species emitting at 540 nm is due only to unbound dye whereas the 660-nm emitting species is due to bound dye. It is, therefore, possible to differentiate unbound acridine orange from its dermatan sulfate complex solely by spectroscopic methods. Thermodynamic binding parameters can be calculated from rapid spectroscopic measurements without disturbing the system.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.1977.360160316
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The hinge-bending mode of a lysozyme-inhibitor complexSupported in part by a grant from the National Institutes of Health. (1986)
    New York : Wiley-Blackwell
    Biopolymers 25 (1986), S. 1767-1802 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The hinge-bending mode of hen egg white lysozyme is studied by a constrained minimization technique. Results with and without a bound inhibitor, tri-N-acetyl-glucosamine, are obtained. The frequency of the mode with the inhibitor is found to be 4.3 cm-1, in contrast to 3.0 cm-1 for the free enzyme. Also, the hinge-bending angle with the lowest energy is shifted 10° towards a more closed cleft in the bound species. The main contribution to these differences arise from interactions with the residues lining the cleft and those on the back side of it. Structural details that account for the energetics are presented. The method of calculation is somewhat different from a previous study [J. A. McCammon, B. R. Gelin, M. Karplus & P. G. Wolynes, (1976) Nature 262, 325-326] to reduce the likelihood of artifacts in the results.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360250916
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Prediction of the folding of short polypeptide segments by uniform conformational sampling (1987)
    New York : Wiley-Blackwell
    Biopolymers 26 (1987), S. 137-168 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A procedure, CONGEN, for uniformly sampling the conformational spaceof short polypeptide segments in proteins has been implemented. Because thetime required for this sampling grows exponentially with the number of residues, parameters are introduced to limit the conformational space that has to be explored. This is done by the use of the empirical energy function ofCHARMM [B. R. Brooks, R. E. Bruccoleri, B. D. Olafson, D. J. States, S. Swaminathan and M. Karplus (1983) J. Comput. Chem. 4, 187-217] and truncating the search when conformations of grossly unfavorable energy are sampled. Tests are made to determine control parameters that optimize the search without excluding important configurations. When applied to known protein structures, the resulting procedure is generally capable of generating conformations where the lowest energy conformation matches the known structure within a rms deviation of 1 Å.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360260114
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Notiz zur Synthese Eines Optisch Aktiven Ace-Hemmers mit Amino-oxo-benzazepin-1-alkansäure-Struktur mittels enantiokonvergierender kristallisationsinduzierter Racemat-Trennung (1988)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 71 (1988), S. 337-343 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Note on the Synthesis of an Optically Active ACE Inhibitor with Amino-oxo-benzazepine-1-alkanoic-Acid Structure by Means of an Enantioconvergent Crystallization-Based ResolutionAn enantioselective synthesis of the potent angiotensin-converting enzyme inhibitor (1′S,3S)-3-[(1′-(ethoxy-carbonyl)-3′-phenylpropyl)amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride (3) is described which user a crystallization-based resolution of a racemic amino intermediate with concomitant racemization of the unwanted enantiomer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19880710205
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Diels-Alder Approach to Highly Functionalized Tertiary α-Hydroxy Ketones: A Novel Route to the Hexahydrobenzofuran Portion of the Avermectins and Milbemycins (1986)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 69 (1986), S. 1273-1286 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A highly regio- and stereoselective Diels-Alder reaction between dienophiles of type I and dienes of type II (Scheme 1) gives rise to Diels-Alder adducts of type III. Upon treatment with BF3.Et2O, these adducts are smoothly converted into the corresponding enones (Scheme 6). Under mild acidic conditions, enone (±)-33 gave bicyclic diketone (±)-34 via an intramolecular Michael-type addition. Diketone (±)-34 has the correct relative configuration and a suitable ketone function at C(6) for further conversion into the hexahydrobenzofuran portion of the avermectins and milbemycins.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19860690602
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Tg-Composition analysis of miscible polymer blends (1988)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 28 (1988), S. 1355-1361 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Several authors have suggested a monotonic variation of the glass transition temperature (Tg) of miscible polymer blends as a function of composition. They usually express the results in terms of equations proposed by Couchman-Karasz, Gordon-Taylor, Fox, and several others. However, we have noticed that numerous systems exhibit a cusp when Tg is plotted as a function of composition (after correction for the presence of crystallinity when semi-crystalline polymers are involved). This cusp cannot appear when the Tg's of the two homopolymers involved are separated by less than about 52 degrees., It will be shown that this observation is quite general since it has been observed with several polyester/chlorinated polymer blends, polycaprolactone/nitrocellulose blends, and polystyrene/poly(vinylmethylether) blends; It will also be shown that this behavior is predicted in the framework of the free volume theory, with equations derived by Kovacs. According to this theory, above a critical concentration φc (relative to the plasticizer) and below a critical temperature Tc, the high-Tc, polymer no longer contributes to the free volume of the mixture whereas it does above Tc. This difference leads to a Tg-composition variation which has to be expressed by two different equations, one below Tc and the other above Tc, the cusp defining the limit of applicability of each equation.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760282104
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    La fusion et la cristallisation de la poly(α,α-diéthyl-β-propiolactone): Comparaison avec d'autres polylactones (1979)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 180 (1979), S. 769-783 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Measurements of crystallization kinetics were made for a sample of poly(α,α-diethyl-β-propiolactone) (DEPL) (syst. name: poly(oxy-2,2-diethyl-1-oxotrimethylene)). An Avrami exponent of 2 was found indicating a two-dimensional growth rate of the crystal, following a pre-determined and heterogeneous nucleation mode. Two melting peaks were found for most samples. The second melting peak (at high temperatures) is probably due to the re-crystallization of part of the sample initially present under the first melting peak. A value of 21kJ.mol-1 was also determined for the heat of fusion of DEPL by the diluent method. This value leads to a degree of crystallinity of 17% which is about four times smaller than that found for poly(pivalolactone) (syst. name: poly(oxy-2,2-dimethyl-1-oxotrimethylene)). We have also determined an equilibrium melting temperature of 531 K for this polymer and an entropy of fusion of 40J.mol-1. K-1. Finally, the surface free energies σ and σe for the lamellar crystals were found to be 12.10-7J.cm-2 and 72.10-7J.cm-2, respectively.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1979.021800320
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Electric field effects on a liquid-crystalline side chain polymer with a negative dielectric anisotropy (1985)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 186 (1985), S. 2407-2414 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The behavior of methacrylic side chain polymers in an electric field was observed for a homopolymer (1) exhibiting a negative dielectric anisotropy compared with a copolymer (2) of positive dielectric anisotropy. Homopolymer 1 orients spontaneously homeotropic and thus enables the determination of the threshold voltage, rise time and decay time. Based on these experimental results the bend elastic constant and viscosity coefficient were estimated using literature values for the dielectric anisotropy. With respect to the bend elastic constant and electrohydrodynamic effects (e.g. Williams Domains) the homopolymer behaves similarly to low-molar-mass liquid crystals, while owing to the high viscosity coefficient response times are large in magnitude.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1985.021861121
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...