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  • 1985-1989
  • 1975-1979  (2)
  • Closure  (1)
  • Kawasaki's disease  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Virchows Archiv 374 (1977), S. 27-44 
    ISSN: 1432-2307
    Schlagwort(e): Coronary artery aneurysms ; Mucocutaneous lymph node syndrome ; Kawasaki's disease ; Infantile polyarteritis nodosa
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In recent years large numbers of the so-called “mucocutaneous lymph node syndrome” or “Kawasaki's disease” have been described by Japanese workers, but instances of this disorder are only now being reported as isolated cases by European or North American physicians. The disease has, therefore, been considered to be a new entity. One of its most striking features is the development of aneurysms of the coronary arteries in infants or children, which may lead to sudden death. Aneurysms of the coronary arteries in childhood are rare, and hence it was considered relevant to report six such cases, and to examine their possible relationship to Kawasaki's disease. The pathological changes underlying the latter disorder are not well known; they are considered to be indistinguishable from infantile polyarteritis nodosa. A diagnosis of polyarteritis nodosa was also thought to be most likely to apply in the cases presented here, particularly in view of the frequency with which aneurysms of the coronary arteries have been found in this disorder. In the absence of valid pathological distinctions between Kawasaki's disease and infantile polyarteritis nodosa, the question arises whether these entities are, in fact, different, and whether Kawasaki's disease is the new entity it is assumed to be.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    European journal of pediatrics 128 (1978), S. 247-259 
    ISSN: 1432-1076
    Schlagwort(e): Umbilical artery ; Birth ; Neonatal ; Blood vessel ; Structure ; Closure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The structure of the fully-patent umbilical artery and rearrangement of its structural elements with postnatal closure were examined in 10 centimeter long umbilical cord segments which were double-clamped at different time intervals after delivery. The fully-patent umbilical artery consists of two main layers: an outer layer of circularly arranged smooth muscle cells and an inner layer which shows rather irregularly and loosely arranged cells embedded in abundant metachromatic ground substance. No predominantly longitudinal arrangements of cells and fibers reported by earlier investigators could be identified in the inner layer. Closure of the umbilical arteries is initiated by numerous localized contractions which are mainly formed by muscle cells of the outer circular layer. Ultimate closure of larger segments of the umbilical arteries is also mainly produced by contractions of the outer layer. In contrast, the inner layer (which is rich in ground substance) seems to serve mainly as a plastic tissue which can easily be shifted in an axial direction and then folded into the narrowing lumen to complete closure. Electron microscopy reveals that the cells of this layer represent rather poorly differentiated smooth muscle cells which contain only a few tiny myofilaments and can therefore hardly contribute actively to the process of closure.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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