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  • 1985-1989  (7)
  • 1975-1979
  • Occupational Health and Environmental Toxicology  (4)
  • Maximum oxygen uptake  (3)
  • 1
    ISSN: 1439-6327
    Keywords: Respiratory exchange ratio ; Maximum oxygen uptake ; Dietary manipulation ; Maximal incremental exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study examined the effects of dietary manipulation upon the respiratory exchange ratio ( $$R = \dot V_{{\text{CO}}_{\text{2}} } /\dot V_{{\text{O}}_{\text{2}} } $$ ) as a predictor of maximum oxygen uptake ( $$\dot V_{{\text{O}}_{{\text{2}} {\text{max}}} } $$ ). Seven healthy males performed fixed term maximal incremental treadmill exercise after an overnight fast on three separate occasions. The first test took place after the subjects had consumed their normal mixed diet (45±5% carbohydrate (CHO)) for a period of three days. This test protocol was then repeated after three days of a low CHO diet (3±2% CHO), and again after three days of a high CHO diet (61±5% CHO). Respiratory gases were continuously monitored during each test using an online system. No significant changes in mean exercise oxygen uptake ( $$\dot V_{{\text{O}}_{\text{2}} } $$ ), $$\dot V_{{\text{O}}_{{\text{2}} {\text{max}}} } $$ or maximum functional heart rate (FHRmax) were found between tests. Mean exercise carbon dioxide output ( $$\dot V_{{\text{CO}}_{\text{2}} } $$ ) and R were significantly lower than normal after the low CHO diet (bothp〈0.001) and significantly higher than normal after the high CHO diet (bothp〈0.05). Moreover, compared with the normal CHO diet, the R-time relationship during exercise was at all times significantly (p〈0.001) shifted to the right after the low CHO diet, and shifted to the left, being significantly so (p〈0.05) over the final 5 min of exercise, after the high CHO diet. As a result, predictions of $$\dot V_{{\text{O}}_{{\text{2}} {\text{max}}} } $$ based on the R-time relationship were similar to recorded $$\dot V_{{\text{O}}_{{\text{2}} {\text{max}}} } $$ after the normal CHO dietary condition (-1.5±1.9%), but higher after the low CHO diet (+14.8±3.9%,p〈0.001) and lower after the high CHO diet (−7.0±4.5%,p〈0.01). These results indicate that dietary manipulation can significantly affect respiratory gas exchanges during fixed term maximal incremental exercise, and by doing so can significantly influence predictions of $$\dot V_{{\text{O}}_{{\text{2}} {\text{max}}} } $$ based on R.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 57 (1988), S. 714-719 
    ISSN: 1439-6327
    Keywords: Respiratory $$\dot V_{CO_2 } /\dot V_{O_2 }$$ exchange ratio ; Incremental exercise ; Treadmill ; Maximum oxygen uptake ; Prediction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The purpose of this study was to define carefully the dynamic relationship between oxygen uptake (as% $$\dot V_{O_{2\max } }$$ ) and the respiratory $$\dot V_{CO_2 } /\dot V_{O_2 }$$ exchange ratio (R) during maximum progressive treadmill exercise in trained and untrained men, and to determine if this relationship could be used to predict $$\dot V_{{\text{O}}_{{\text{2max}}} } $$ . Respiratory gases were continuously monitored and the % $$\dot V_{{\text{O}}_{{\text{2max}}} } $$ /R time profile calculated at 15 sec intervals over the final 5 min of each test. Young sedentary men (controls,n = 122) and over −60y sedentary men (n = 30) shared the same % $$\dot V_{{\text{O}}_{{\text{2max}}} } $$ /R relationship but the latter group had lower R values at $$\dot V_{{\text{O}}_{{\text{2max}}} } $$ (1.06±0.03 vs 1.08±0.03,P〈0.01) than controls. Endurance trained men (n = 45) had a lower % $$\dot V_{{\text{O}}_{{\text{2max}}} } $$ /R relationship and higher R at $$\dot V_{O_{2\max } }$$ (1.11±0.02,P〈 0.001), team athletes (n = 98) had a lower% $$\dot V_{O_{2\max } }$$ /R relationship but lower R at $$\dot V_{O_{2\max } }$$ (1.06±0.03,P〈0.001) and the weight trained (n = 19) had a higher% $$\dot V_{O_{2\max } }$$ /R relationship and lower R at $$\dot V_{O_{2\max } }$$ (1.01±0.02,P〈 0.001) all compared to controls. From the % $$\dot V_{O_{2\max } }$$ /R time profile, the following formulae were devised for the estimation of $$\dot V_{O_{2\max } }$$ ( $$\dot V_{O_{2\max } }$$ R): Young Sedentary, $$\dot V_{O_{2\max } }$$ R = $$\dot V_{O_2 }$$ R (3.000 −1.874 R); Over −60y Sedentary, $$\dot V_{O_{2\max } }$$ R = $$\dot V_{O_2 }$$ R (3.457-2.345 R); Endurance Trained, $$\dot V_{O_{2\max } }$$ = $$\dot V_{O_2 }$$ R (1.980–0.912 R); Team Athletes, $$\dot V_{O_{2\max } }$$ R = $$\dot V_{O_2 }$$ R (2.805−1.726 R); Weight Trained, $$\dot V_{O_{2\max } }$$ R = $$\dot V_{O_2 }$$ R (4.236−3.191 R). Comparison of recorded $$\dot V_{O_{2\max } }$$ and the estimated $$\dot V_{O_{2\max } }$$ R values showed no significant differences in any of the groups examined (r = 0.89–0.90,p〈 0.001). These results suggest the R response to maximum incremental exercise may be influenced by different types of physical training, and that specific formulae derived from the % $$\dot V_{O_{2\max } }$$ /R relationship can provide a precise estimate of $$\dot V_{O_{2\max } }$$ for individuals.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1439-6327
    Keywords: Respiratory $$\dot V_{CO_2 } /\dot V_{O_2 }$$ exchange ratio ; Maximum oxygen uptake ; Maximum exercise ; Prediction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study examined the effect of previous severe exercise upon (i) respiratory exchange during maximal exercise, and (ii) the respiratory $$\dot V_{CO_2 } /\dot V_{O_2 }$$ exchange ratio (R) as a predictor of maximum oxygen uptake ( $$\dot V_{O_{2\max } }$$ )- Thirteen healthy males performed a progressive treadmill test to $$\dot V_{O_{2\max } }$$ : at rest (T1); after a 1 h run on the level treadmill at a speed corresponding 82.4±7.3% of their $$\dot V_{O_{2\max } }$$ (T2); after 1 h recovery (T3); and after 24 h recovery (T4). Respiratory gases were continuously monitored. No changes in average work $$\dot V_{O_2 }$$ , $$\dot V_{O_{2\max } }$$ or maximum heart rate were found between trials. Average work $$\dot V_{CO_2 }$$ was lower in T2 (2.055±0.093 l·min−1,p〈0.001), T3 (2.080±0.087 l·min−1,p〈0.001) and T4 (2.337±0.154 l·min−1, NS) compared with T1 (2.360±0.147 l·min−1). This resulted in lower average R values in T2 (0.81±0.02,P〈0.001), T3 (0.83±0.02,P〈0.001) and T4 (0.94±0.02, NS) in relation to T1 (0.95±0.02). Analysis of the % $$\dot V_{O_{2\max } }$$ /R relationship over the final 5 min of each test showed a shift to the left during T2 (p〈0.001), T3 (p〈0.001) and T4 (NS) compared with T1. As a result predictions of $$\dot V_{O_{2\max } }$$ based on R ( $$\dot V_{O_{2\max } }$$ R) were similar to recorded $$\dot V_{O_{2\max } }$$ in T1 (+0.6%) and T4 (+2.2%). But higher in T2 (+8.7%,p〈0.001) and T3 (+6.9%,p〈0.001). The present results show that previous severe exercise can significantly affect respiratory exchange at rest and during maximum incremental exercise, and by doing so can significantly influence predictions of $$\dot V_{O_{2\max } }$$ based on R.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 7 (1986), S. 405-414 
    ISSN: 0197-8462
    Keywords: temperature ; hyperthermia ; Evans-blue ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: The combined effects of ethanol and microwaves on the permeation of Evans blue dye through the mammalian blood-brain barrier was studied in male Wistar rats. Anesthetized rats were infused through a cannula in the left femoral vein with 0.1, 0.3, 0.5 or 0.7 grams of absolute ethanol per kilogram of body mass. A control group was given 0.7 g/kg of isotonic saline. The left hemisphere of the brain was irradiated by 3.15-GHz microwave energy at 3.0 W/cm2 rms for 15 min. The rat's rectal temperature was maintained at 37.0°C. Immediately after irradiation, 2% Evans blue dye in saline (2.0 ml/kg body mass) was injected through the cannula. The results show that as the quantity of alcohol was increased, the degree of staining was decreased or eliminated. The temperature of the irradiated area of the brain increased for the first 4 to 5 minutes of irradiation and then stabilized for the remainder of the irradiation period. The steady-state temperature was highest in animals receiving saline or the smallest dose of alcohol. As the quantity of alcohol was increased, the steady-state temperature was reduced. These results indicate that ethanol inhibits microwave-induced permeation of the blood-brain barrier through reduced heating of the brain.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 9 (1988), S. 141-147 
    ISSN: 0197-8462
    Keywords: microwave pulses ; acoustic pressure ; speed of propagation ; attenuation coefficient ; frequency spectrum ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: This paper presents direct measurements of acoustic pressure wave propagation in cat brains irradiated with pulsed 2.45-GHz microwaves. Short rectangular microwave pulses (2 μs, 15 kW peak power) were applied singly through a direct-contact applicator located at the occipital pole of a cat's head. Acoustic pressure waves were detected by using a small hydrophone transducer, which was inserted stereotaxically into the brain of an anesthetized animal through a matrix of holes drilled on the skull. The measurements clearly indicate that pulsed microwaves induce acoustic pressure waves which propagate with an acoustic wave velocity of 1523 m/s.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 7 (1986), S. 209-221 
    ISSN: 0197-8462
    Keywords: brain tissue ; radiofrequency ; radiation ; dosimetry ; calcium ions ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: This paper presents calculations for the electric field and absorbed power density distribution in chick brain tissue inside a test tube, using an off-center spherical model. It is shown that the off-center spherical model overcomes many of the limitations of the concentric spherical model, and permits a more realistic modeling of the brain tissue as it sits in the bottom of the test tube surrounded by buffer solution. The effect of the unequal amount of buffer solution above the upper and below the lower surfaces of the brain is analyzed. The field distribution is obtained in terms of a rapidly converging series of zonal harmonics. A method that permits the expansion of spherical harmonics about an off-center origin in terms of spherical harmonics at the origin is developed to calculate in closed form the electric field distribution. Numerical results are presented for the absorbed power density distribution at a carrier frequency of 147 MHz. It is shown that the absorbed power density increases toward the bottom of the brain surface. Scaling relations are developed by keeping the electric field intensity in the brain tissue the same at two different frequencies. Scaling relations inside, as well as outside, the brain surface are given. The scaling relation distribution is calculated as a function of position, and compared to the scaling relations obtained in the concentric spherical model. It is shown that the off-center spherical model yields scaling ratios in the brain tissue that lie between the extreme values predicted by the concentric and isolated spherical models.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 6 (1985), S. 257-270 
    ISSN: 0197-8462
    Keywords: microwaves ; noise modulation ; temperature ; snail neurons ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Helix aspersa neurons were irradiated with continuous-wave (CW) and noise-amplitudemodulated microwaves (carrier frequency 2450 MHz, 20% AM, 2 Hz-20 kHz) in a specially designed waveguide exposure system. Continuous-wave microwave irradiations were conducted at 8°, 21°, and 28°C, while noise-modulated irradiation was performed at 21°C. The results showed that exposure of snail neurons to CW microwaves for 60 min at 12.9 W/kg inhibited spontaneous activity and reduced input resistance at 8° and 21°C but not at 28°C. The relative decrease in resistance at 21°C was half that at 8°C. Exposure of neurons to noise-modulated microwaves at 6.8 and 14.4 W/kg predominately caused excitatory responses characterized by augmented membrane resistance and the appearance of greater activity. The effect differed qualitatively from the inhibition observed with continuous, unmodulated microwave irradiation.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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