ISSN:
1420-9071
Keywords:
Luffolide
;
Luffariella sp
;
X-ray structure determination
;
anti-inflammatory
;
phospholipase A2
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Luffolide (4) is a minor metabolite of the spongeLuffariella sp. from Palau. The structure of luffolide was determined by single crystal X-ray analysis. Luffolide is relatively unstable and undergoes a complex cyclization reaction to give the hexacyclic products5 and6. Luffolide (4) has some of the anti-inflammatory properties of manoalide (1): this may help to define the chemical reaction between manoalide (1) and phospholipase A2.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01957489
Permalink