Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Anatomia, histologia, embryologia
17 (1988), S. 0
ISSN:
1439-0264
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The distal radial growth plates of six pairs of spider-affected and non-affected lambs were compared after light and electron microscopic evaluation. Light microscopy revealed regions within the spider-affected physes that lacked the distinctly columnized appearance of the normal ones. However, provisional calculation as revealed by von Kossa staining did not differ between the two groups; nor were there marked ultrastructural differences between control and spider lamb growth plate chondrocytes or matrices. The spider growth plates were also studied after concanavalin A and wheat germ agglutinin lectin histochemistry. Intracellular and extracellular staining patterns did not differ from previously reported normal patterns. Finally, SDS-PAGE analysis of collagen extracted in the native state from spider-affected cortical bone revealed that it is comprised of type I collagen that is normal in its primary structure; furthermore, there is no type III collagen present.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1439-0264.1988.tb00567.x
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