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  • 1985-1989  (4)
  • 1975-1979  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Oxygen content control for as-deposited YBa2Cu3Ox thin films by oxygen pressure during rapid cooling following laser deposition (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 55 (1989), S. 899-901 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: As-deposited epitaxial YBa2Cu3Ox thin films have been prepared by ArF excimer laser deposition followed by a rapid cooling with controlled oxygen pressure. The best film after the rapid cooling has a Tc with a zero resistance of 88 K and a Jc (77 K) of 5.5×105 A/cm2. It has been observed that the c-lattice parameter decreases, that is, the oxygen content x increases from ∼6 to 7, with increasing oxygen pressure during the rapid cooling. The relation between x and oxygen pressure is almost consistent with that for a powder sample being in a thermal equilibrium. We conclude that the oxygen content in the as-deposited films is determined by the thermal equilibrium oxygen content during the cooling process.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.102449
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  • 2
    Digitale Medien
    Digitale Medien
    Quantitative Cytological Analysis of Functional Changes in Adrenomedullary Chromaffin Cells in Normal, Sham-Operated, and Pinealectomized Rats in Relation to Time-of-day: II. Nuclear-Cytoplasmic Ratio, Nuclear Size, and Pars Granulosa of Nucleolus (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 5 (1988), S. 0 
    Details
    ISSN: 1600-079X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Adrenaline(A)- and noradrenaline(N)-cells in the adrenal medulla of nonoperated (NO), sham-operated (SO), and pinealectomized (PX) male rats (n = 125) were investigated by quantitative electron and light microscopy. Animals were killed at eight time points during a standardized 24-h, light-dark (12:12) cycle 14 days after surgery. Nuclear-cytoplasmic (N/P) ratios, diameters of nuclei, and the frequency of nucleoli showing a large amount of pars granulosa (granulated nucleoli), were the primary characteristics studied.Major findings include the following: 1) The frequency of low N/P ratios over a 24-h period tended to be higher in PX animals than in controls in A-cells, as shown in large cell profiles (P 〈 0.02); but such a tendency was not apparent in N-cells. Daily mean nuclear diameters were similar among the three experimental groups. 2) The 24-h changing pattern of phase relations in the frequency of low N/P ratio and nuclear size differed between A- and N-cells in NO and SO but not in PX animals. 3) The frequency of granulated nucleoli in A-cells was much higher in PX animals than in NO and SO animals throughout a 24-h period (P 〈 0.018), especially from the late light to early dark phase (P 〈 0.003), and higher in A-cells than in N-cells generally (P 〈 0.0009). Pinealectomy thus caused increases in the cytoplasm and in the pars granulosa of the nucleolus in many A-cells; changes in N-cells were less apparent. This suggest a disturbed balance and coordination between A- and N-cell systems of adrenal medulla following pinealectomy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-079X.1988.tb00778.x
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  • 3
    Digitale Medien
    Digitale Medien
    Quantitative Ultrastructural Analysis of Differences in Exocytosis Number in Adrenomedullary Adrenaline Cells of Golden Hamsters Related to Time of Day, Pinealectomy, and Intracellular Region (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 2 (1985), S. 0 
    Details
    ISSN: 1600-079X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: This research analyzed differences mainly in the incidence of exocytotic figures in adrenaline cells (A - cells) in pinealectomized (PX), sham-operated (SPX), and non-operated (NO) adult male golden hamsters, with the aim of determining whether these parameters change with the time of day and following pinealectomy, and whether intracellular regional differences exist in such changes. Animals acclimated to a standardized light: dark (LD) 12:12 photoperiod were sacrificed at 11 h after the onset of light (L-11h) and 1 h after the onset of darkness (D-1h) (8 animals/group/time) at 28 days postoperation. The adrenal medullas were examined and analyzed morphometrically by electron microscopy. The number of exocytoses per unit length (NEL) and the exocytosis index (a rough index of the number of exocytoses per cell) were measured in PF (perivascular-space-facing) and non-PF plasma membranes. NEL increased from L-11h (NO: 0.040 ± 0.010, X̄± SE) to D-1h (0.078 ± 0.012) in all three experimental groups (ANOVA: P 〈 0.005), showing over fourfold higher levels in PF than in non-PF membranes. NEL in PF membranes in PX animals showed higher levels than those in NO and SPX animals (P 〈 0.025), but in non-PF membranes, no differences owing to time of day or surgery were seen. Exocytosis indices were (1) higher at D-lh than at L-llh in all three experimental groups (P 〈 0.005), (2) similar in PF and non-PF membranes in control groups, and (3) higher in PF membranes in the PX group than in either non-PF membranes or PF membranes in control groups. In conclusion, the exocytosis number in A cells changes in relation to time of day, rising in early dark phase, and its rise following pinealectomy can be seen only in PF membranes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-079X.1985.tb00644.x
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  • 4
    Digitale Medien
    Digitale Medien
    Quantitative Cytological Analysis of Functional Changes in Adrenomedullary Chromaffin Cells in Normal, Sham-Operated, and Pinealectomized Rats in Relation to Time of Day: III. Nuclear Density (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 5 (1988), S. 0 
    Details
    ISSN: 1600-079X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The sizes of adrenaline (A) and noradrenaline (N) cells in the adrenal medulla of nonoperated (NO), sham-operated (SPX), and pinealectomized (PX) male rats (n = 126) were investigated by quantitative light microscopy. Animals were killed at eight time points during a standardized 24-h, light-dark (12:12) cycle 14 days after surgery. Nuclear densities were measured in semithin sections of eponembedded specimens, initially fixed with glutaraldehyde and OsO4. Major findings are as follows. 1) The mean size of adrenomedullary A cells throughout 24 h (P〈0.001), especially in the dark phase (P〈0.001) but not in the light phase, was larger in PX animals than in NO and SPX animals. There were no statistically significant differences in the size of N cells among the three experimental groups in either the dark phase or the light phase. 2) The sizes of A and N cells showed time-of-day changes in the NO and the SPX animals but not in the PX animals. The temporal relationship of 24-h changes in the cell size tended to be different between A and N cells in the NO and the SPX animals but not in the PX animals. 3) The cell size was apparently larger in A cells than in N cells in each experimental group. Pinealectomy thus caused hypertrophy of A cells, especially in the dark phase, but not apparently hypertrophy of N cells. Concerning the pinealectomy effects in relation to the time of day, the results support the hypothesis of pineal action being phase-tuning and coordinating of at least some circadian systems.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-079X.1988.tb00795.x
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  • 5
    Digitale Medien
    Digitale Medien
    Hypothalamic dopamine-β-hydroxylase activity: Fluctuations with time of day and their modifications by intracranial surgery, adrenalectomy, and pinealectomy (1978)
    Springer
    Neurochemical research 3 (1978), S. 281-293 
    Details
    ISSN: 1573-6903
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Hypothalamic and plasma dopamine-β-hydroxylase (DBH, EC 1.14.2.1) activities were measured by a coupled radioenzymatic method. Animals representing five experimental groups (intact controls, adrenalectomized, pinealectomized, adrenalectomized + pinealectomized, doubly sham-operated) were killed and sampled at 8 times through the 24-hr daily cycle, 15 days postoperation, and at 50–52 days of age. Hypothalamic DBH in intact control animals had statistically significant fluctuations in relation to time of day. These changes were lost or dampened in groups that had had intracranial surgery and were characteristically shifted by adrenalectomy, either alone or with pinealectomy. Plasma DBH fluctuations in the same animals resembled those in hypothalamus in some features (e.g., peak near mid-dark; shift in daily maxima and minima after adrenalectomy) and differed in others (e.g., no effect of intracranial surgery or of sham operation; adrenalectomized + pinealectomized animals resembled the solely pinealectomized). Although temporal patterns in hypothalamic DBH activity thus differed in the experimental animal groups, the daily means of hypothalamic DBH activity were similar.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00965575
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