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  • 1985-1989  (1)
  • 1975-1979  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Age-related changes of glucose metabolism in rat cerebral cortex with reference to glucose-derived amino acids (1985)
    Springer
    Neurochemical research 10 (1985), S. 1615-1622 
    Details
    ISSN: 1573-6903
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The parietal cortical slices obtained from 8 week-old (young) and 78 week-old (middle-aged) male Wistar rats were incubated withd-[U-14C]glucose in oxygensaturated Gey's balanced salt solution. Subsequently, the radioactivities of liberated CO2 and glucose-derived amino acids (alanine, aspartate, GABA, glutamate and glutamine) obtained from the slices were measured. In the middle-aged rats as compared to the young rats, the amount of radioactivity of CO2 (P〈0.01) and glutamate (P〈0.05) showed a significant raduction with glutamine unchanged, while that of alanine (P〈0.01), aspartate (P〈0.05) and GABA (P〈0.05) increased significantly. The results indicate that with advancing age the overall glucose oxidation in the cerebral cortex declines but the metabolic pathway to form amino acids is not uniformly suppressed. Therefore, the above characteristic glucose metabolism could be related to the development of heterogeneous enzyme activities associated with aging in the brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00988603
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The structure and innervation of the sinu-atrial node of the mole heart (1976)
    Springer
    Cell & tissue research 172 (1976), S. 345-356 
    Details
    ISSN: 1432-0878
    Keywords: Mole heart ; SA node ; Innervation ; Neuromuscular relationship ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The sinu-atrial node in the heart of the mole, Mogera wogera, contains myocytes which are devoid of atrial specific granules and which may be classified into two types: electron-lucent (majority) and dark (minority). Numerous unmyelinated axon terminals, containing synaptic vesicles, face the nodal myocyte surface with interspaces of less than 300 nm. There are about 6 terminals per myocyte profile and about 10 per profile at nuclear levels. Of a total of 2717 of these terminals 85.2% are 50–200 nm from the nodal myocytes, and 9.6% form closer neuromuscular junctions, with less than 50 nm interspace and some membrane specialization. Such specializations are almost exclusively found in relation to the dark, minority-type of nodal myocyte. Myelinated nerve fibers are also numerous within the mole SA node, and may terminate almost directly on a nodal myocyte. A few nerve fibers contain many mitochondria and may represent afferent endings. Nodal capillaries are smaller and fewer than capillaries in the juxtanodal myocardium, probably indicating a lesser blood supply to the SA node than to the ordinary myocardium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399517
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Mitochondria-rich (chloride) cells in the gill epithelia from four species of stenohaline fresh water teleosts (1977)
    Springer
    Cell & tissue research 180 (1977), S. 87-98 
    Details
    ISSN: 1432-0878
    Keywords: Chloride cell ; Stenohaline freshwater teleosts ; Gill epithelia ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The mitochondria-rich (chloride) cells have been found to be present in the gill epithelia of four species of stenohaline fresh water teleosts. The cytoplasm of these chloride cells contains an extensive network of cytoplasmic tubules which communicate with intercellular spaces bordering the lateral and basal cell surfaces. Numerous vesicles with fairly electron-dense interiors are also present in the apical cytoplasm of chloride cells. The apical surface of a chloride cell forms an apical pit, but the lumen of the pit does not appear to be in continuity with the interior of the apical vesicles and tubules inside the cell. When Carassius auratus were kept in 100, 200, 300, and 400 mOsm-diluted sea water for a month, no appreciable changes occurred in the number and fine structure of the chloride cells, except for a dilation of the apical vesicles and a slight decrease in diameter of the cytoplasmic tubules in these cells in the fishes kept in 300 and 400 mOsm. These results suggest that chloride cells may be a rather common occurrence in the gill epithelia of stenohaline fresh water teleosts, and may function in ion-transport in these fishes in fresh water environments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00227031
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    Paper (German National Licenses)
    Fulltext
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