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  • 1985-1989  (4)
  • 1970-1974  (7)
  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 245 (1973), S. 373-375 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The answer is yes, in view of the higher Ti and Fe in the plume-derived ocean crust. Because oceanic magnetic anomalies are essentially the result of thermoremanent magnetisation carried by finely disseminated titanomag-netite10, a basalt crust with higher Fe and Ti should have higher amplitude ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 240 (1972), S. 338-342 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Volume estimates and age dating of basic, non-orogenic igneous deposits suggest synchronous discharge from many hot spots, identified as mantle plumes. The discharge fluctuations seem to mirror the histories of diverse global geological parameters. Extinction crisis of faunal evolution may reflect ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 239 (1972), S. 79-81 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The Miocene increase of bottom currents in the western North Atlantic is linked to subsidence, by thermal contraction of the cooling lithosphere, of the sills forming the aseismic ridge east and west of ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 234 (1971), S. 22-25 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Magnetic profiles parallel to and between fracture zones in the Cretaceous western Atlantic suggest at least twenty-five reversals between 135 and 90 m.y. BP, with a long normal period between 80 and 90 m.y. BP. The fracture zones constrain the position of the America–Africa ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 226 (1970), S. 743-744 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. Evolution of rifted continental margin in central North Atlantic. The continental basement subsides by erosion, and the disappearance of the thermal anomaly is inherited from the initiation of rifting. Note that the basement reaches sea level 50 to 100 m.y. after the ocean basin forms. ...
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1440
    Keywords: Leukemia ; Lymphoma ; Fever ; Neutropenia ; Mycosis ; Antibiotics, antifungal ; Autopsy ; Retrospective studies ; Comparative studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A rate on autopsy of up to 30% systemic fungal infections and difficulties in diagnosing systemic mycosis antemortem have led to the empiric use of amphotericin B in patients with hematological malignancies, prolonged fever, and neutropenia. Routine empiric antifungal treatment was initiated in our institution in 1982. Amphotericin B was given to granulocytopenic patients with hematological malignancies with (a) unremitting fever after 48–72 h of antibiotic treatment, (b) recurrent fever during antibiotic treatment, or (c) with newly detected pulmonary infiltrates, sinusitis, skin and retinal lesions suggestive of a fungal infection. With this approach the rate of systemic fungal infections decreased significantly from 10% (27 of 270 patients; 1973–1981) to 4% (6 of 153 patients; 1982–1986,P〈0.02). The reduction of systemic fungal infections was most prominent in patients with acute myelogenous leukemia, where its proportion decreased from 16% (16 of 98 patients; 1973–1981) to 4% (2 of 50 patients; 1982–1986,P〈0.023). Our data support the hypothesis that the incidence of systemic fungal infections in patients with hematological malignancies and especially in acute myelogenous leukemia can be reduced significantly by empirical treatment with amphotericin B.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 241 (1973), S. 189-191 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 Simplified sketches of major aseismic ridges and seamount chains near island arcs of the Pacific and Indian oceans, based on standard bathymetric charts and the new north Pacific atlas8. Plate collision boundaries shown by single or double lines, the latter showing both volcanic arc and ...
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 97 (1989), S. 429-433 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The condensation of the Y chromosome in mouse cells was studied with two repetitive DNA probes, pY353/B and M34. Both DNA probes are specific to the Y chromosome and hybridize in situ along the whole chromosome. Due to the high resolution of the in situ hybridization technique with non-radioactive labeled DNA probes it was possible to observe the degree of condensation of the Y chromosome in the interphase cell nuclei of various somatic tissues and on testes preparations. The Sertoli cells were the only cell type in which the Y chromosome was always observed to be in a highly decondensed state. The decondensation of the Y chromosome in the Sertoli cells supports the view that the genetic activity of the Y chromosome is cell autonomous and opens the way to its molecular analysis.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Ocean dynamics 24 (1971), S. 49-73 
    ISSN: 1616-7228
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Description / Table of Contents: Zusammenfassung Vermessungen, die kürzlich vom U.S. Naval Oceanographic Office durchgeführt worden sind, haben sehr dazu beigetragen, das Wissen über die primären und sekundären Prozesse zu erweitern, die die derzeitige Morphologie des nordöstlichen Teiles des Atlantischen Ozeans und der Labrador-See geschaffen haben. Primäre Prozesse werden direkt der Entstehung von ozeanischer Kruste an der Achse des Mittelatlantischen Rückens zugeschrieben. Wechselnde Richtungen der Achse haben drei verschieden orientierte getrennte Streifen ozeanischer Kruste seit 60 Millionen Jahren hervorgebracht. Der Augenschein läßt vermuten, daß eine noch ältere Achse verantwortlich gewesen sein kann für das Öffnen zwischen Labrador-See und Biscaya Bucht im frühen Mesozoikum. Sekundäre Prozesse haben die vulkanische Kruste verändert und tun dieses noch. Die Hauptwirkungskraft ist eine starke thermo-haline Zirkulation, die in manchen Gebieten Ablagerungen in großen Streifen aufhäuft und an anderen Stellen Erosionen verursacht.
    Abstract: Résumé De récentes explorations effectuées par l'U.S. Naval Océanographic Office ont grandement enrichi notre connaissance des processus primaire et secondaire qui sont à l'origine de la morphologie actuelle de l'Atlantique Nord-Est et de la mer du Labrador. Les processus primaires remontent directement à la création de croûte océanique dans l'axe de la chaîne océanique médiane. Des changements d'orientation de l'axe ont donné naissance à trois bandes discontinues, d'orientations différentes, de la croûte océanique depuis 60 millions d'années. On est en droit de penser qu'un axe, plus ancien encore, a provoqué l'ouverture mer du Labradorgolfe de Gascogne au messzoïque supérieur. Des processus secondaires ont modifié — et continuent de modifier — la croûte ignée. Le facteur le plus important est une forte circulation thermo-haline qui entasse les sédiments en grandes masses en certaines zones et, ailleurs, en entraîne l'érosion.
    Notes: Summary Recent surveys by the US Naval Oceanographic Office have added greatly to the knowledge of the primary and secondary processes which have created the present morphology of the northeastern Atlantic and Labrador Sea. Primary processes are directly attributed to the generation of oceanic crust at the axis of the Mid-Oceanic Ridge. Shifting orientations of the axis have produced three differently oriented discrete stripes of oceanic crust since 60 million years ago. Evidence suggests a yet older axis may have been responsible for the opening of the Labrador Sea-Bay of Biscay in the early Mesozoic. Secondary processes have and are still modifying the igneous crust. The prime agent is a strong thermo-haline circulation which is piling up sediment into great plumes in some areas and eroding in other locales.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Infection 16 (1988), S. 175-178 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden 42 Nierentransplantat-Empfänger wegen Harnwegsinfektionen mit Ofloxacin oral behandelt. 39 Patienten erhielten Ciclosporin A, drei Patienten Azathioprin, jeweils in Kombination mit Prednisolon zur Immunsuppression. Bei allen Patienten wurden vor, während und nach der Ofloxacin-Therapie Laborparameter routinemäßig untersucht, unter besonderer Berücksichtigung nephrotoxischer Erscheinungen bzw. möglicher Interaktionen mit der begleitenden immunsuppressiven Medikation. In der vorliegenden Studie erwies sich Ofloxacin als sicheres und effektives Antibiotikum in der Behandlung von Harnwegsinfektionen bei nierentransplantierten Patienten ohne nachweisbare Nephrotoxizität oder toxische Interferenzen mit Ciclosporin A bzw. Azathioprin.
    Notes: Summary Forty-two renal transplant recipients suffering from complicated urinary tract infection (UTI) were treated orally with ofloxacin. Patients received an immunosuppressive treatment consisting of ciclosporin A and prednisolone (n=39) or azathioprine and prednisolone (n=3). Patients were routinely controlled for laboratory parameters before, during and after ofloxacin administration with special emphasis on nephrotoxicity and interaction of ofloxacin with the concomitantly administered immunosuppressives. Results show that ofloxacin does not impair renal graft function or interact with ciclosporin A or azathioprine even under long-term administration. It is effective and safe in the treatment of UTI in the renal transplant recipient.
    Type of Medium: Electronic Resource
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