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  • 1
    Electronic Resource
    Electronic Resource
    Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis (1988)
    Springer
    Cellular and molecular life sciences 44 (1988), S. 230-232 
    Details
    ISSN: 1420-9071
    Keywords: Honebee hive ; propolis ; caffeic acid ester ; cytoxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The honeybee hive product, propolis, is a folk medicine employed for treating various ailments. Many important pharmaceutical properties have been ascribed to propolis, including anti-inflammatory, antiviral, immunostimulatory and carcinostatic activities. Propolis extracts have provided an active component identified as caffeic acid phenethyl ester (CAPE), which was readily prepared in one step. Differential cytotoxicity has been observed in normal rat/human versus transformed rat/human melanoma and breast carcinoma cell lines in the presence of CAPE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01941717
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Genetic diversity among sublines originating from a single somatic hybrid cell of Duboisia hopwoodii + Nicotiana tabacum (1988)
    Springer
    Theoretical and applied genetics 76 (1988), S. 641-646 
    Details
    ISSN: 1432-2242
    Keywords: Duboisia hopwoodii ; Nicotiana tabacum ; Somatic hybrid ; Nuclear DNA content ; Genetic instability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The genetic instability of an intertribal hybrid cell line, Duboisia hopwoodii + Nicotiana tabacum, obtained by mechanical isolation of a single hybrid cell was studied. Ten subclones of calli derived from this hybrid cell line were cultured for 3 years, and their genetic makeup clarified as to nuclear DNA content, chromosome constitution, and peroxidase isozymes. Nuclear DNA content differed in each subclone. In most subclones, mean DNA content was lower than the mean DNA content in the original hybrid cell line determined 1 year after fusion. This decrease in DNA content is partly attributable to the elimination of tobacco chromosomes that occurred in all subclones. The extent to which tobacco chromosomes were eliminated varied among the subclones — evidence that chromosome elimination occurred slowly. Peroxidase isozyme analysis indicated the loss of a tobacco-specific isozyme, thus confirming results obtained by chromosome analysis. Shoots regenerated from two hybrid subclones after 2 years were also heterogeneous in morphology and nuclear DNA content.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00303507
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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