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  • 1
    Electronic Resource
    Electronic Resource
    Antimutagenic unusual amino acids from plants (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1622-1623 
    Details
    ISSN: 1420-9071
    Keywords: Antimutagens ; natural product ; unusual amino acids ; isolation and structural determination ; Liliaceae ; Sapindaceae ; Salmonella typhimurium TA100
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Five unusual amino acids were identified as antimutagens against spontaneous mutation ofSalmonella typhimurium TA100: L-azetidine-2-carboxylic acid (1) from Liliaceae plants, α-(methylenecyclopropyl)glycine (2) fromLitchi chinensis seeds, and 2-amino-4-methylhex-5-ynoic acid (3), hypoglycin A (4), and (2S, 4R)-2-amino-4-hydroxyhept-6-ynoic acid (5) fromEuphoria longana seeds. The absolute stereochemistry of5 was determined by its chiral synthesis from L-allylglycine, proving that5 is the C-4 epimer of the amino acid previously isolated from dried longan seeds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01964840
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Genetic diversity among sublines originating from a single somatic hybrid cell of Duboisia hopwoodii + Nicotiana tabacum (1988)
    Springer
    Theoretical and applied genetics 76 (1988), S. 641-646 
    Details
    ISSN: 1432-2242
    Keywords: Duboisia hopwoodii ; Nicotiana tabacum ; Somatic hybrid ; Nuclear DNA content ; Genetic instability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The genetic instability of an intertribal hybrid cell line, Duboisia hopwoodii + Nicotiana tabacum, obtained by mechanical isolation of a single hybrid cell was studied. Ten subclones of calli derived from this hybrid cell line were cultured for 3 years, and their genetic makeup clarified as to nuclear DNA content, chromosome constitution, and peroxidase isozymes. Nuclear DNA content differed in each subclone. In most subclones, mean DNA content was lower than the mean DNA content in the original hybrid cell line determined 1 year after fusion. This decrease in DNA content is partly attributable to the elimination of tobacco chromosomes that occurred in all subclones. The extent to which tobacco chromosomes were eliminated varied among the subclones — evidence that chromosome elimination occurred slowly. Peroxidase isozyme analysis indicated the loss of a tobacco-specific isozyme, thus confirming results obtained by chromosome analysis. Shoots regenerated from two hybrid subclones after 2 years were also heterogeneous in morphology and nuclear DNA content.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00303507
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    Paper (German National Licenses)
    Fulltext
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