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Digitale Medien

Antimutagenic unusual amino acids from plants (1985)

Minakata, H. ; Komura, H. ; Tamura, S. Y. ; [weitere]

Springer

Cellular and molecular life sciences 41 (1985), S. 1622-1623

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Details

ISSN: 1420-9071

Schlagwort(e): Antimutagens ; natural product ; unusual amino acids ; isolation and structural determination ; Liliaceae ; Sapindaceae ; Salmonella typhimurium TA100

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary Five unusual amino acids were identified as antimutagens against spontaneous mutation ofSalmonella typhimurium TA100: L-azetidine-2-carboxylic acid (1) from Liliaceae plants, α-(methylenecyclopropyl)glycine (2) fromLitchi chinensis seeds, and 2-amino-4-methylhex-5-ynoic acid (3), hypoglycin A (4), and (2S, 4R)-2-amino-4-hydroxyhept-6-ynoic acid (5) fromEuphoria longana seeds. The absolute stereochemistry of5 was determined by its chiral synthesis from L-allylglycine, proving that5 is the C-4 epimer of the amino acid previously isolated from dried longan seeds.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01964840

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