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  • 1
    Electronic Resource
    Electronic Resource
    Osteosarcoma in irradiated fibrous dysplasia (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 15 (1986), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case is described of Osteosarcoma arising in a pre-existing fibrous dysplasia fifty years after radiotherapy for facial hirsutism. The patient was treated by surgical excision and chemotherapy and is alive and free of disease five years later.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1986.tb00555.x
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  • 2
    Electronic Resource
    Electronic Resource
    Improvement of Neuromuscular Transmission by 3,4-Diaminopyridine in the Lambert-Eaton Myasthenic Syndrome and in Myasthenia Gravis (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 505 (1987), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1987.tb51367.x
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  • 3
    Electronic Resource
    Electronic Resource
    Diffusion and Activity in Computerized Enzyme Electrode Systems (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 501 (1987), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1987.tb45725.x
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  • 4
    Electronic Resource
    Electronic Resource
    Fully discrete approximation methods for the estimation of parabolic systems and boundary parameters (1986)
    Springer
    Acta applicandae mathematicae 7 (1986), S. 1-34 
    Details
    ISSN: 1572-9036
    Keywords: 41A15 ; 65N30 ; Parabolic systems ; parameter estimation ; approximation methods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A spatially and temporally discrete numerical approximation scheme is developed for the identification of a class of semilinear parabolic systems with unknown boundary parameters. The identification problem is formulated as a least squares fit to data subject to an equivalent representation for the dynamics in the form of an abstract evolution equation. Finite-dimensional difference equation state approximations are constructed using a cubic spline-based, Galerkin method and the Padé rational function approximations to the exponential. A sequence of approximating identification problems result, the solutions of which are shown to exist and, in a certain sense, approximate solutions to the original identification problem. Numerical results for two examples, one involving the modeling of biological mixing in deep sea sediment cores, and the other, the estimation of transport parameters for indoor mixing, are discussed. In both examples, the identification is based upon actual experimental data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00046975
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  • 5
    Electronic Resource
    Electronic Resource
    Functional organization of the spinoreticulocerebellar path with identification of its spinal component (1966)
    Springer
    Experimental brain research 1 (1966), S. 306-319 
    Details
    ISSN: 1432-1106
    Keywords: Lateral reticular nucleus ; Reticulocerebellar tract ; Spinoreticular tract ; Cerebellum ; Flexor reflex afferents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Mass discharges were recorded from the dissected left restiform body in unanaesthetized, decerebrate, and decerebellate cats. The spinal cord was severed in the thoracic or cervical region sparing only the left ventral quadrant. In this preparation the discharges were shown to relate largely or exclusively to activity in the reticulocerebellar tract originating from the lateral reticular nucleus. The ascending spinal tract was identified with the bilateral ventral flexor reflex tract (bVFRT) of Lundberg and Oscarsson (1962). The reticulocerebellar tract was activated from the flexor reflex afferents and nerve volleys from each of the four limbs were equally effective. It is concluded that the lateral reticular nucleus is not responsible for the somatotopically organized projection of cutaneous afferents, as assumed before. The bVFRT is strongly influenced from the cerebellar cortex and the organization of the closed loop formed between the cortex and the spinal cord is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237703
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  • 6
    Electronic Resource
    Electronic Resource
    Response characteristics of retieulocerebellar neurones activated from spinal afferents (1966)
    Springer
    Experimental brain research 1 (1966), S. 320-328 
    Details
    ISSN: 1432-1106
    Keywords: Lateral reticular nucleus ; Reticulocerebellar tract ; Spinoreticular tract ; Cerebellum ; Flexor reflex afferents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The experiments were done on unanaesthetized, decerebrate, and decerebellate cats. Recording was made from axons originating in the lateral reticular nucleus on stimulation of various nerves, cutaneous receptors, and certain descending tracts. Excitatory and inhibitory effects were evoked from the flexor reflex afferents of receptive fields which included most of the body surface. It is concluded that the lateral reticular nucleus with respect to its afferent inflow is similar to the non-cerebellar nuclei of the reticular formation. The possibility that the reticulocerebellar tract is important in determining the background excitation of cortical neurones is discussed. The effects evoked by stimulation of descending tracts were consistent with the disclosure that the bilateral ventral flexor reflex tract is the afferent path to the lateral reticular nucleus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237704
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  • 7
    Electronic Resource
    Electronic Resource
    Intravenous physostigmine treatment of Alzheimer's disease evaluated by psychometric testing, regional cerebral blood flow (rCBF) measurement, and EEG (1987)
    Springer
    Psychopharmacology 93 (1987), S. 31-35 
    Details
    ISSN: 1432-2072
    Keywords: Physostigmine treatment ; Alzheimer's disease ; Regional cerebral blood flow (rCBF) ; EEG ; Psychometric testing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ten patients with Alzheimer's disease were treated with intravenous infusion of physostigmine for 2 h. The acute effects on cognitive function, regional cerebral blood flow, and EEG were compared to placebo (isotonic glucose) using a double-blind cross-over design. Physostigmine causes a limited improvement of psychomotor performance and EEG and an increase of blood flow in the most severely affected cortical areas, predominantly in an early phase of Alzheimer's disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02439583
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  • 8
    Electronic Resource
    Electronic Resource
    Improvement in Neuromuscular transmission in Myasthenia Gravis by 3,4-Diaminopyridine (1985)
    Springer
    European archives of psychiatry and clinical neuroscience 234 (1985), S. 374-377 
    Details
    ISSN: 1433-8491
    Keywords: 3,4-Diaminopyridine ; Neuromuscular transmission ; Myasthenia gravis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 3,4-Diaminopyridine (3,4-DAP), a potent potentiator of action potential evoked release of acetylcholine from presynaptic terminals in the neuromuscular junction was given i.v. and p.o. to two patients with myasthenia gravis. Effects were monitored electrophysiologically by repetitive nerve stimulation and by standardized clinical testing. Administration of 8 mg and 9 mg 3,4-DAP i.v. produced a clear improvement in the neuromuscular transmission after approximately 20 min. When 3,4-DAP was given p.o. 24 mg was shown to be effective. At a dosage of 18–24 mg p.o. 3,4-DAP significantly potentiated the effect of the cholinesterase inhibitor pyridostigmine at an optimal dose. The maximal effect of 3,4-DAP p.o. was obtained after 2.5–3 h. No significant CNS side-effects were found which is in contrast to those reported for 4-aminopyridine. The results suggest that 3,4-DAP may be useful as an addition to the conventional treatment with cholinesterase inhibitors when immunosuppressive treatment is considered contraindicated or when it has not yet reached its full effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00386054
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