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  • 1
    Electronic Resource
    Electronic Resource
    Reversible changes in the nucleosomal organization of a human H4 histone gene during the cell cycle (1986)
    s.l. : American Chemical Society
    Biochemistry 25 (1986), S. 5364-5370 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00367a003
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  • 2
    Electronic Resource
    Electronic Resource
    Coordinate turnover of nuclear and cytoplasmic histone messenger RNA following inhibition of DNA replication in HeLa S3 cells (1987)
    s.l. : American Chemical Society
    Biochemistry 26 (1987), S. 2938-2944 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00384a040
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  • 3
    Electronic Resource
    Electronic Resource
    Gum Rosin Modified with β-Propiolactone in Unsaturated Polysters (1963)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 2 (1963), S. 182-185 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/i360007a003
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  • 4
    Electronic Resource
    Electronic Resource
    Mechanism of the Oxidation and Reduction of Metal Ions by Hydrogen Atoms (1960)
    [s.l.] : Nature Publishing Group
    Nature 186 (1960), S. 629-630 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] For the oxidation of Fe2+ (reaction 1) we propose the following mechanism : ¿3 Fe2+ + H ^ FeH2+ (3) FeH2+ Fe3 ¿4 Ht w A detailed kinetic analysis9 shows this mechanism to be in quantitative accord with the observed7 dependence of the rate on the Fe2+ and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/186629a0
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  • 5
    Electronic Resource
    Electronic Resource
    Action of Low Doses of Ionizing Radiations on the Electrophoretic Mobility of Ehrlich Ascites Tumour Cells (1962)
    [s.l.] : Nature Publishing Group
    Nature 193 (1962), S. 238-239 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] PREVIOUS investigators1 have shown that the electrophoretic mobility of Ehrlich ascites tumour colls is reproducible. The cells, washed under controlled conditions (3 washes, at 25 C. in 0-145 M aqueous sodium chloride made 3 x 1O4 M with respect to sodium bicarbonate pH. 7-0 ± 0-2) and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/193238a0
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  • 6
    Electronic Resource
    Electronic Resource
    The structure of bis[(R,S)-N,N'-bis(5-methyl-2-thienylmethylene)-1,2-cyclohexanediamine]copper(I) trifluoromethanesulfonate, C36H44CuN4S4+.CF3SO3− (1985)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 41 (1985), S. 374-377 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270185003961
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  • 7
    Electronic Resource
    Electronic Resource
    Zur Klinik kavernöser Hämangiome an Haut und inneren Organen (1964)
    Springer
    Archives of dermatological research 218 (1964), S. 177-190 
    Details
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Das nicht zu seltene Auftreten von Hämangiomen an der Haut und an inneren Organen wurde zum Anlaß genommen, die verschiedene Lokalisation der Hämangiome, die Alters- und Geschlechtsverteilung, die Diagnose, Prognose und Therapie zu untersuchen. Wegen der schlechten Prognose wurden die Larynxhämangiome und die großen, in die Tiefe reichenden Hals-Nackenhämangiome der Säuglinge ausführlicher dargestellt. Der klinische Verlauf eines derartig lokalisierten Hämangioms an einem eigenen Patienten wird erläutert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00510976
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  • 8
    Electronic Resource
    Electronic Resource
    A series of repetitive DNA sequences are associated with human core and H1 histone genes (1985)
    Springer
    Molecular and cellular biochemistry 67 (1985), S. 161-170 
    Details
    ISSN: 1573-4919
    Keywords: histone genes ; globin gene cluster ; repetitive sequences ; sequence organization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary Repetitive DNA sequences, derived from the human β-globin gene cluster, were mapped within a series of human genomic DNA segments containing core (H2A, H2B, H3 and H4) and H1 histone genes. Cloned recombinant λCH4A phage with human histone gene inserts were analyzed by Southern blot analysis using the following32P-labeled (nick translated) repetitive sequences as probes:Alu I,Kpn I and LTR-like. A cloned DNA designated RS002-5′C6 containing (i)a (TG)16 simple repeat, (ii) an (ATTTT)n repeat and (iii)a 52 base pair alternating purine and pyrimidine sequence was also used as a radiolabelled hybridization probe. Analysis of 12 recombinant phage, containing 6 arrangements of core histone genes, indicated the presence ofAlu I,Kpn and RS002-5′C6 repetitive sequences. In contrast, analysis of 4 human genomic DNA segments, containing both core and H1 histone genes, indicated the presence of onlyAlu I family sequences. LTR-like sequences were not detected in association with any of the core or H1 histone genes examined. These results suggest that human histone and β-globin genes share certain aspects of sequence organization in flanking regions despite marked differences in their overall structure and pattern of expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02370175
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  • 9
    Electronic Resource
    Electronic Resource
    Nucleosomal organization of a BPV minichromosome containing a human H4 histone gene (1987)
    Springer
    Molecular and cellular biochemistry 74 (1987), S. 173-177 
    Details
    ISSN: 1573-4919
    Keywords: chromatin ; episome ; histone gene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract To address the relationship between chromatin structure and histone gene expression, the nucleosomal organization of a cell cycle-dependent human H4 histone gene in a bovine papilloma virus (BPV) minichromosome was examined. The nucleosome repeat length of the human H4 histone gene, maintained as a stable episome in a C127 mouse cell line designated 1–8 [1], was compared with that of the chromosomal copy of the H4 gene in human (HeLa) cells. In both cell lines, the H4 histone gene is predominantly expressed during the S phase of the cell cycle. The nucleosome repeat length of total HeLa cell and C127 mouse cell chromatin was similarly examined. Nuclei were digested with micrococcal nuclease and the DNA was fractionated electrophoretically, transferred to nitrocellulose filters and hybridized with radiolabelled (32P) cloned DNA probes. The nucleosome repeat length of the H4 gene, as an episome in the C127 mouse cell (153 ± 8) and as an integrated copy in a HeLa cell (163 ± 10) was considerably shorter than total genomic host cell (C127) (190 ± 5) or HeLa cell chromatin (183 ± 7). Our results indicate that the episomal H4 histone gene is packaged as chromatin. Moreover, the shortened nucleosome repeat length of the H4 gene, both as an episome or integrated chromosome sequence, suggests that the repeat length is characteristic of the gene and may be functionally related to its cell cycle regulated expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224955
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  • 10
    Electronic Resource
    Electronic Resource
    Virulence properties of escherichia coli strains in patients with chronic pyelonephritis (1986)
    Springer
    Infection 14 (1986), S. 145-150 
    Details
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 50Escherichia coli-Stämmen, die aus dem Blasenpunktionsurin von Patienten mit chronischer Pyelonephritis gewonnen wurden, erfolgten Bestimmungen ihrer Virulenzeigenschaften. In den 26 Fällen mit einer akuten Erkrankung fanden sich ausschließlich S-Formen der Bakterien, K 1 Antigen wurde in 30% nachgewiesen, 77% verfügten über die Fähigkeit zur Hämolysinbildung und 30% über die zur Colicin V (Aerobactin)-Produktion. In 70% fanden sich Plasmidspezies der Größe zwischen 50 und 70 Md. Demgegenüber wurden bei den 24 Patienten mit einem inaktiven Stadium der Pyelonephritis nur in 70% derE. coli-Stämme S-Formen gefunden. Bei ihnen konnten in 10% K 1 Antigen, in 20% Hämolysin und in 10% Colicin V bestimmt werden. Plasmide zwischen 50 und 70 Md. lagen in 30% der Bakterienstämme vor. Nach der multivariaten Varianz- und Diskriminanzanalyse bestätigt sich, daß uropathogene Bakterienstämme über mehrere Virulenzeigenschaften verfügen müssen, dabei kommt der Fähigkeit zur mannoseresistenten Hämagglutination eine besondere Bedeutung zu.
    Notes: Summary In 50Escherichia coli strains obtained from the bladder puncture urine of patients with chronic pyelonephritis, determinations of virulence properties were performed. All of theE. coli strains isolated from 26 acute episodes of pyelonephritis were found in the smooth form. 30% possessed K 1 antigen, 77% showed the ability to form hemolysin and 30% produced colicin V (aerobactin). Fimbriae (detected by mannose-resistant hemagglutination) were registered in 81%, and plasmids ranging between 50 and 70 Md were demonstrated in 70% of the bacteria. In contrast to this, only 70% of theE. coli strains isolated from 24 patients at an inactive stage of pyelonephritis were found in the smooth form; 10% of these encoded K 1 antigen, 20% hemolysin and 10% colicin V. Plasmids in the range 50 to 70 Md could be found in 30%. On the basis of multivariate analysis of variance and discriminant analysis, it was confirmed that uropathogenic strains possess several virulence properties, mannose-resistant hemagglutination being of particular importance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01643482
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