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  • 1985-1989  (1)
  • 1960-1964  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    Esophageal acid clearance during sleep in patients with Barrett's esophagus (1988)
    Springer
    Digestive diseases and sciences 33 (1988), S. 654-659 
    Details
    ISSN: 1573-2568
    Keywords: gastroesophageal reflux ; sleep ; Barrett's esophagus ; acid clearance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sleep-related gastroesophageal reflux and esophageal acid clearance have been shown to be important components in the pathogenesis of reflux esophageal disease. Previous studies have suggested that patients with more severe esophagitis are distinguished by an accumulation of acid mucosal contact time during sleep. These data would suggest that patients with Barrett's esophagus should have particularly severe impairment of acid clearance, most notable during sleep. To address this issue, 16 asymptomatic healthy volunteers and 13 patients with Barrett's esophagus were studied. Acid clearance was assessed by timing the reestablishment of an esophageal pH of 4 following the infusion of 15 ml 0.1 N HCl. Sleep was poly graphically monitored in order to objectively determine sleep and waking. The results indicated that while patients with Barrett's esophagus had a marked increase in the frequency of spontaneous gastroesophageal reflux during sleep, they unexpectedly demonstrated faster acid clearance times during both waking and sleep. A greater percentage of arousal responses to acid infusion during sleep was noted in the Barrett's group. It is concluded from these results that patients with Barrett's esophagus can adequately clear acid from the distal esophagus but experience considerable acid mucosal contact through repeated episodes of spontaneous reflux during sleep.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01540426
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Vascular responses in the exposed human colon (1960)
    Springer
    Digestive diseases and sciences 5 (1960), S. 579-602 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02290192
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Portal cirrhosis in alcoholic and nonalcoholic women (1962)
    Springer
    Digestive diseases and sciences 7 (1962), S. 84-92 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. During a 10-year period 59 women with portal cirrhosis were hospitalized at the University of Oklahoma Hospital. Approximately half of the patients were alcoholic. Twenty-one of the nonalcoholic and 12 of the alcoholic women and diagnoses of portal cirrhosis supported by examination of hepatic tissue. These 33 patients with tissue diagnosis are compared in detail. 2. The alcoholic women were younger at the onset of their symptoms and were commonly from urban areas. The initial clinical diagnosis on these patients was usually cirrhosis, since they frequently had the symptoms, physical findings, and abnormal hepatic function tests associated with this disease. 3. The nonalcholic women were on the average older at the onset of their symptoms. Since they usually had abdominal pain and ascites without many of the expected physical findings of cirrhosis, their initial clinical diagnoses were frequently incorrect. Arterial hypertension or other extrahepatic disease occurred in the majority. A high index of suspicion and a liver biopsy are needed to make the diagnosis in these patients. 4. The possible etiologic factors leading to cryptogenic portal cirrhosis in the nonalcoholic women are discussed briefly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02231934
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Colon blood flow (1963)
    Springer
    Digestive diseases and sciences 8 (1963), S. 614-622 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary and Conclusion 1. The intramural blood vessels of the human colon have been described. 2. Five methods that have been used to study colonic mucosal blood flow in patients with colostomies or with normal colons were briefly outlined along with some of the limitations of each technic. 3. It has been shown that the colonic mucosal blood flow in the human responds to heating or cooling an extremity, eating a meal, pharmacologic agents, and emotionally stressful situations. 4. Adequate evaluation of colonic mucosal blood flow requires the development of quantitative technics of measurement. It may be that methods of monitoring radioactive indicators with critically shielded detectors may meet some of these needs16 and offer a way of studying the intact colon of an unanesthetized human subject.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02239458
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Nondialyzable B12 binding material in human gastric juice following histamine stimulation (1964)
    Springer
    Digestive diseases and sciences 9 (1964), S. 246-255 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02232129
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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