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  • 1
    Electronic Resource
    Electronic Resource
    The pattern of basal and stimulated insulin responses to intravenous glucose in first degree relatives of Type 1 (insulin-dependent) diabetic children and unrelated adults aged 5 to 50 years (1988)
    Springer
    Diabetologia 31 (1988), S. 430-434 
    Details
    ISSN: 1432-0428
    Keywords: Insulin ; glucose ; age ; children ; puberty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pattern of insulin secretion was studied in 107 normal individuals aged 5 to 50 years. Intravenous glucose tolerance tests were performed on 64 islet-cell antibody negative siblings of diabetic children and on 43 normal adults. Puberty was staged using Tanner's criteria and subjects were grouped as follows: I — stage 1 (n=22), II — stages 2 and 3 (n=18), III — stages 4 and 5 (n=20), IV — adults 〉17 years (n=47). Basal and stimulated (incremental 0–10 and 10–60 min areas) insulin responses rose throughout puberty (Groups I–III), declined following puberty until the third decade (Groups III and IV) and then appeared constant thereafter. Insulin levels in the 17.6–22.5 year group were lower than in the 12.6–15 year group (p〈0.01). Fasting insulin to glucose ratios and incremental 0–60 min insulin to glucose area ratios produced a similar age-related pattern indicating that changes in insulin levels were independent of glucose concentrations. Gender did not affect these changes and multiple regression analysis showed that HLA haplotype sharing did not influence insulin responses in siblings of diabetic patients. Age and pubertal status must be carefully considered when interpreting intravenous glucose tolerance tests from patients suspected of having early abnormalities of carbohydrate metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271587
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  • 2
    Electronic Resource
    Electronic Resource
    Gradient recalled echo MR imaging of superior sagittal sinus occlusion (1989)
    Springer
    Neuroradiology 31 (1989), S. 134-136 
    Details
    ISSN: 1432-1920
    Keywords: Gradient recalled echo ; MRI ; Sinus occlusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary With T1-weighted gradient recalled echo (GRE) MR images and flow compensation, we studied the superior sagittal sinus in 3 normal volunteers and 3 patients with sinus occlusion. In these images, sites of patency of the superior sagittal sinus were identified due to the high signal intensity of the normal sinus. Tumor invading the sinus was nearly isointense with cerebral gray matter. T1-weighted GRE imaging proves to be an effective technique to evaluate sinus blood flow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00698840
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Technical factors in MR image quality (1986)
    Springer
    Neuroradiology 28 (1986), S. 74-77 
    Details
    ISSN: 1432-1920
    Keywords: Head ; MRI ; Image quality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied the subjective rating of MR image quality as field strength, slice thickness, number of acquisitions and matrix size were varied. Matrix and number of acquisitions had the most significant effect on image quality. Therefore, in comparisons of image quality, technique must not be disregarded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341772
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  • 4
    Electronic Resource
    Electronic Resource
    Single-crystal electron-spin resonance study of the 4-phenyl-1,2,3,5-dithiadiazolyl radicalNRCC No. 30635. (1989)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 27 (1989), S. 1161-1165 
    Details
    ISSN: 0749-1581
    Keywords: Electron spin resonance ; Electron paramagnetic resonance ; Free radical ; π-Radical ; Heterocyclic free radical ; g Tensor ; Hyperfine interaction tensor ; Nitrogen hyperfine interaction ; Dithiadiazolyl ; Dithiadiazolylium ; Dithiadiazolium ; Unpaired electron ; Unpaired electron spin density ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Single crystals of 4-phenyl-1,2,3,5-dithiadiazolium trithiatriazinide , prepared by the reduction of S5N5+AlCl4- in SO2 with , contain a trace paramagnetic impurity which is shown by EPR spectroscopy to be the dithiadiazolyl free radical . The g and 14N hyperfine tensors of the radical were deduced from measurements made throughout three mutually orthogonal planes of crystallographically aligned specimens: g = (2.0011, 2.0075, 2.0197); 14N(2) = (37.1, 11.3, 3.4 MHz.). Within experimental error, the two nitrogen hyperfine interaction tensors are collinear and have their maximum principal value aligned parallel to gmin and perpendicular to the plane of the host cation. The results are interpreted in terms of a planar π-radical which substitutes for the planar host cation, and which has considerable unpaired spin density in N(2px) atomic orbitals directed perpendicular to the heterocyclic ring.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1260271210
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    Paper (German National Licenses)
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