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  • 1985-1989  (2)
  • 1900-1904
  • Engineering  (1)
  • Morphometry  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 277 (1985), S. 457-465 
    ISSN: 1432-069X
    Keywords: Epidermis ; Hyperplasia ; TPA ; Stereology ; Morphometry ; Tumor promotors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 12-O-Tetradecanoylphorbol-13-acetate (TPA)-treated adult epidermis as well as untreated fetal and adult epidermis were investigated to elucidate the effect of TPA in terms of cell differentiation using techniques of ultrastructural stereology. Twenty-four hours after a single application of TPA, the treated epidermis was characterized by involutional changes, i. e., increased volume density of intercellular spaces and of mitochondria, vacuoles, and cytoplasmic ground substance in the basal layer. However, 48 h after application, the TPA-treated epidermis was very similar to fetal epidermis, i. e., high volume density of nuclei ribosomes, rough endoplasmic reticulum, membrane-coating granules, and keratohyalin granules, and low volume density of bundled filaments in the upper layers. These stereological data indicate that the changes observed 48 h after TPA treatment were related not only to increased cell proliferation but also to inhibition of cell differentiation expressed as a reversion of the adult differentiation patterns and the acquisition of fetal characteristics in all epidermal layers.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Communications in Applied Numerical Methods 1 (1985), S. 113-121 
    ISSN: 0748-8025
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A traction boundary condition is particularly useful when analysing flow governed by the Navier-Stokes equation. For a large range of flow situations, such as fully developed laminar flow in a pipe or far field flow, the values of boundary traction can be evaluated explicitly. The former can be readily determined from the local values of the primitive variables, while the latter corresponds to zero traction. A general approach is advocated where traction boundary conditions can be evaluated as part of the solution procedure and its value is not required, a priori, before the solution can proceed. An iterative procedure for the evaluation and imposition of non-zero tractions on boundaries, where advection is appreciable, is demonstrated by utilizing the finite element method (FEM) to simulate laminar flow, both steady state and transient, rearward of a downstream-facing step within a bounded domain.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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