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Elevated intracranial pressure associated with hypermetabolism in isolated head trauma (1988)

Bucci, M. N. ; Dechert, R. E. ; Arnoldi, D. K. ; [et al.]

Springer

Acta neurochirurgica 93 (1988), S. 133-136

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ISSN: 0942-0940

Keywords: Head injury ; intracranial pressure ; metabolism ; nitrogen balance ; oxygen consumption

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Both metabolic rate and protein catabolism are known to increase following severe head trauma, but the etiology of this hypermetabolism is unknown. To further investigate the problem, we studied the metabolism of 17 patients with indirect calorimetry who had severe craniocerebral trauma only and who required ICP monitoring for management. Patients were studied daily and immediately after ICP spikes greater than 20 mmHg, prior to treatment with hyperventilation, osmotic diuretics, or barbiturates. Oxygen consumption (VO2) was correlated with ICP. Two groups of patients were identified. Group I patients were treated with hyperventilation and osmotic diuretics while Group II patients additionally received cerebral metabolic depressants. Group I had a significant correlation coefficent between VO2 and ICP. Significant hypercatabolism early in the post trauma period was demonstrated by increased urine urea nitrogen. Our observations suggest that in patients with craniocerebral trauma, elevated ICP is associated with increased oxygen consumption, protein catabolism and systemic hypermetabolism. Cerebral metabolic depressants blunted increases in VO2 which were seen with elevated ICP.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01402895

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Effect of impurities on emulsion polymerization: Case II kinetics (1988)

Huo, B. P. ; Campbell, J. D. ; Penlidis, A. ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Polymer Science 35 (1988), S. 2009-2021

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ISSN: 0021-8995

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics

Notes: The effects of water-soluble and monomer-soluble impurities on the kinetics of emulsion polymerization of monomers following Case II kinetics (e.g., styrene) are investigated. Experimental studies reveal that impurities can have an appreciable effect on both polymer particle nucleation and growth. These effects are shown to be well predicted by a mathematical model.

Additional Material: 9 Ill.