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  • 1985-1989  (2)
  • Bovine adenovirus type 3  (1)
  • Electrical impedance plethysmography  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Acta neuropathologica 66 (1985), S. 218-222 
    ISSN: 1432-0533
    Schlagwort(e): Choroid plexus papilloma ; Giant cell glioblastoma ; Bovine adenovirus type 3 ; Hamster
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Newborn hamsters were inoculated with 0.02 ml of bovine adenovirus type 3 (BAV 3) having a titer of 104.5TCID50/0.1 ml. Of 82 hamsters observed over 40 days after viral inoculation, 15 developed choroid plexus papilloma after a latency period of 41–228 days and six developed giant cell glioblastoma after a latency period of 66–214 days. Multiple foci of abnormal cell grwoth were also observed in the meninges and choroid plexus. Choroid plexus papilloma developed in the ventricles occupying the ventricular cavity and histologically showed a radiating arrangement of spindle-shaped cells forming perivascular pseudorosettes. Giant cell glioblastoma developed in the cerebral cortex including the meninges. The tumors were reddish in color and soft in consistency. Histologically, the tumor cells were short-spindle, ovar or, pleomorphic cells with a large vesicular nucleus, and were characterized by the appearance of monster cells and hypervascularity. The short spindle-shaped cells were positive for glial fibrillary acid protein.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Medical & biological engineering & computing 25 (1987), S. 386-390 
    ISSN: 1741-0444
    Schlagwort(e): Central caudal artery ; Electrical impedance plethysmography ; Electromagnetic flowmetry ; Peripheral blood flow ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract The impedance Z, the derivative of Z with respect to time t, dZ/dt, and blood flow F have been measured simultaneously in the central caudal artery of a series of anaesthetised rats. The results of the experiments were expressed in the relationship derived from the Windkessel theory where f(t)=adz(t)/dt+βz(t), in which α and β are constants and f(t) and z(t) express the pulsating fractions in the blood flow F and the impedance Z, respectively. The correlation between the peak-to-peak values of f(t) and of adz(t)/dt+βz(t) was 0·96. The correlation between the mean flow fo and the peak-to-peak value of f(t) was 0·74. Furthermore, even when the mean flow was zero, adz(t) still existed. The theoretical model was tested against volume flow measurements made using an electromagnetic flowmeter and was found to correlate well. Theoretical estimates of vessel calibre also accord with measured values.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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