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  • 1985-1989  (2)
  • gliomas  (1)
  • stingless bees  (1)
  • CNS tumor
  • Caste
  • 1
    Electronic Resource
    Electronic Resource
    Formic acid in caustic cephalic secretions of stingless bee,Oxytrigona (Hymenoptera: Apidae) (1987)
    Springer
    Journal of chemical ecology 13 (1987), S. 1079-1086 
    Details
    ISSN: 1573-1561
    Keywords: Defensive secretions ; formic acid ; Oxytrigona ; Hymenoptera ; Apidae ; stingless bees ; mandibular glands ; Meliponinae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The cephalic extracts of two species in the stingless bee genusOxytrigona were analyzed. Extracts made in diethyl ether, and then derivatized with diphenyldiazomethane, revealed large quantities of formic acid, potentially a major defensive secretion of this stingless bee group. We additionally identify several hydrocarbons, aldehydes, ketones, and acetates. Novel diketones identified by others were detected in both species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01020539
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Glucose metabolism in human gliomas: Correspondence ofin situ andin vitro metabolic rates and altered energy metabolism (1986)
    Springer
    Metabolic brain disease 1 (1986), S. 279-291 
    Details
    ISSN: 1573-7365
    Keywords: energy metabolism ; glia ; gliomas ; positron emission computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The rates of disappearance of glucose from the medium of 13 human glioma-derived cell lines and one cultured of normal human cortical astrocytes were determined by ftuorometric techniques. High-grade glioma-derived cultures showed a range of glucose consumption between 1 and 5 nmol/min/mg protein. Normal astrocyte cultures and cultures derived from grades I–III gliomas had a glucose consumption rate of 2–3 nmol/min/mg protein. Seven high-grade glioma lines were derived from surgical samples taken from patients who had been scanned by18F-2-deoxy-d-glucose positron computed tomography. The rate of glucose consumption in these high-grade glioma-derived lines was close to the maximum local cerebral metabolic rate for glucose (LCMRglc) measuredin situ in the tumors from which the cultures were derived. In cultured glioma-derived lines, approximately one-half of the glucose consumed was recovered as lactate and pyruvate, suggesting a reliance of glioma cells on aerobic glycolysis. ATP and phosphocreatine (PCr) levels were variable in the gliomaderived lines, and ATP was lower in the glioma-derived lines than in the normal astrocytes. Levels and regulation of glycogen differed significantly among the various glioma-derived cell lines. Glycogen content did not diminish as glucose was consumed, suggesting that glycogen utilization is not tightly regulated by the glucose metabolic rate. These results suggest that human glioma-derived cell cultures (1) adequately reflect the metabolic capacity of gliomasin situ and (2) are significantly altered in several aspects of their glycolytic metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00999357
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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