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  • 1985-1989  (4)
  • Cholecystokinin  (1)
  • Cyclic oxidation  (1)
  • Phe-tRNA synthetase  (1)
  • oxidation resistance  (1)
  • yttrium addition  (1)
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Years
  • 1985-1989  (4)
Year
Keywords
  • 1
    ISSN: 1476-5535
    Keywords: Fermentation development ; Cholecystokinin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The natural product asperlicin is the first nonpeptide antagonist of cholecystokinin isolated from a microbial source. At discovery, production of asperlicin by the original soil isolate ofAspergillus alliaceus was between 15 and 30 mg/l. Selection of natural variants ofA. alliaceus, use of Plackett & Burman and Simplex experimental designs; formulation of synthetic media; amino acid supplementation of production media; analysis of complex nitrogen sources for their amino acid content; evaluation of promising media in fermentors; substitution of glycerol for glucose as a carbon source and rational mutant selection all contributed to titer increases to 〉900 mg/l.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-4889
    Keywords: Cyclic oxidation ; nodule ; oxidation resistance ; nodular growth ; wart
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The effect of small concentrations of zirconium on the cyclic oxidation behavior of Fe-15Cr-4Al was investigated at 1300°C. The zirconium concentrations studied were 0.2, 0.55, and 1 wt.%. Each cycle consisted of a 1-hr isothermal period followed by 30-min cooling of the sample in air. Nodule formation was observed in higher zirconium-containing alloys, 0.55% and 1% zirconium, and the base alloy. The nodules formed at the corners and edges of the specimen and grew with increasing number of cycles. EDAX and line scans of cross section of oxidized samples demonstrated that the nodules were composed of iron oxides. Suggestions are given regarding the mode of nodule formation. Results show that additions of 0.2% zirconium and 1% yttrium to the base alloy suppress the nodule formation and provide the best resistance to cyclic oxidation.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-4889
    Keywords: Kinetics ; yttrium addition ; sulfidation ; sulfides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract High-temperature sulfidation studies have been carried out on Fe-15Cr-4Al with and without 1% Y in the temperature range 700–1000°C in an H 2-H2 S environment over the sulfur pressure range of 10 −9−10−3 atm. Two-layered and three-layered sulfide scales were observed in both alloys at low and high sulfur pressures, respectively. The pegging phenomenon, similar to that occurring in high-temperature oxidation, across the innermost layer and substrate was observed in the case of the yttrium-containing alloy. Yttrium was found to be associated with aluminum and chromium sulfides. The role of yttrium was more evident at low than at high sulfur pressures and was found to reduce the parabolic rate constants by a factor of about one-half to one-seventh, respectively.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 209 (1987), S. 164-169 
    ISSN: 1617-4623
    Keywords: Aspergillus nidulans ; p-Fluorophenylalanine ; Resistant mutants ; Phe-tRNA synthetase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We have isolated and characterized a new class of p-fluorophenylalanine (FPA)-resistant mutant in Aspergillus nidulans using a phenA strain as the wild type, by optimizing the conditions of growth. All four spontaneous mutants selected on a medium containing FPA were found to be recessive to their wild-type alleles in heterozygous diploids. Complementation analyses and linkage data showed that they were allelic and mapped at a single locus (fpaU) in the facA-riboD interval on the right arm of linkage group V. Partial purification and characterization of Phe-tRNA synthetase from wild-type and mutant strains revealed that the mutant enzyme had a greatly reduced ability to activate the analogue. It is suggested that mutation in the fpaU gene brings about a structural alteration in Phe-tRNA synthetase.
    Type of Medium: Electronic Resource
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