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  • 1985-1989  (2)
  • Choline acetyltransferase  (1)
  • Electron microscopy  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Do folliculo-stellate adenomas of the pituitary gland exist or are they intrasellar meningiomas? (1988)
    Springer
    Acta neuropathologica 77 (1988), S. 219-223 
    Details
    ISSN: 1432-0533
    Keywords: Meningioma ; Folliculo-stellate cell ; Pituitary neoplasm ; Electron microscopy ; Immunochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A tumor arising in the pituitary fossa and having some of the histological and ultrastructural features of a recently described tumor, purportedly originating from the folliculo-stellate cells of the anterior pituitary, is presented. The results of our ultrastructural and immunohistochemical studies, however, favored a meningeal origin and suggested that the neoplasm was most likely a secretory meningioma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687435
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Diffuse Lewy body disease (1987)
    Springer
    Acta neuropathologica 75 (1987), S. 8-15 
    Details
    ISSN: 1432-0533
    Keywords: Choline acetyltransferase ; Lewy body ; Parkinson's disease ; Somatostatin ; Thioflavine S
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Post-mortem pathological and biochemical studies are reported on six patients with progressive dementia. The characteristic pathological finding was neurofilament-containing cytoplasmic inclusions in cortical and subcortical neurons. The clinical and pathological findings were consistent with so-called diffuse Lewy body disease. The patients had variable changes of the Alzheimer type, with five of six patients displaying “plaques only” Alzheimer's changes. Biochemical studies showed profound decreases in neocortical choline acetyltransferase (ChAT) activities that correlated with marked neuronal loss in the basal nucleus of Meynert. ChAT activities were normal in the hippocampus in three patients who also had no significant Alzheimer type hippocampal changes. All patients had decreased cortical somatostatin-like immunoreactivity. Our observations suggest that dementia in diffuse Lewy body disease bears biochemical similarities to Alzheimer's disease, in that biochemical markers for both intrinsic cortical neurons and ascending cholinergic neurons are affected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00686786
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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