ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Reactions of N-(N′,N′-Dialkyl(aryl)amino-thiocarbonyl)benzimidoylchlorides with Potassium ThiocyanateThe treatment of the title compound N-(amino-thiocarbonyl)-benzimidoylchloride 1 with potassium thiocyanate leads in dependence on the solvents (methanol, acetic acid, acetone) either to the 1,3,5-thiadiazine-2-thione 2a-d or to the ring opened isothiocyanate 4a, b. In the case of methanol the N-(amino-thiocarbonyl)benzimidates were formed as by-products.The structure of the products is confirmed by analytical data and by chemical transformations. 2a reacts with methyl iodide to form the 2-methylthio-6-morpholino-4-phenyl-1,3,5-thiadiaziniumiodide 3a. From 4a and water the N-(morpholino-thiocarbonyl)benzamide 5a arises. The reaction of morpholine with 4a yields the benzamidine 6a.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19883300210
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