ISSN:
1432-0584
Keywords:
HTLV-III antibodies
;
AIDS
;
lymphadenopathy syndrome
;
homosexuals at risk of AIDS
;
ELISA
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In a first seroepidemiological study on the prevalence of the human T-lymphotropic retrovirus HTLV-III in West Germany, sera of 26 patients with acquired immunodeficiency syndrome (AIDS), 33 patients with lymphadenopathy syndrome (LAS) or AIDS related complex (ARC), and 113 homosexual men at risk of AIDS were screened for IgG antibodies to HTLV-III by an enzyme linked immunosorbent assay (ELISA). 22 out of 26 AIDS-patients (84.6%), 24 out of 33 LAS-patients (72.7%), and 44 out of 113 healthy homosexual men with increased risk of AIDS (38.9%) were found positive for antibodies to HTLV-III. Heterosexual controls including healthy laboratory workers and medical personnel with contact to AIDS patients did not show antibodies to HTLV-III. The HTLV-III antibodies analyzed predominantly recognize a protein of molecular weight 41,000 (p 41).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00319764
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