ISSN:
1432-1459
Keywords:
Alzheimer's disease
;
Somatostatin
;
Endocrine system
;
Amyloid
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Recent data suggest a disturbance of some brain somatostatin neurons in Alzheimer's disease. Moreover, some endocrine activities known to be regulated by somatostatin, such as growth hormone, thyroid-stimulating-hormone, somatomedins, as well as insulin and glucose metabolism, also seem to be affected in some patients. It is speculated that these changes are due to a global CNS and endocrine somatostatin defect in Alzheimer's disease and that the described endocrine imbalance may indirectly be responsible for at least part of the CNS pathology.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00313925
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