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  • 1985-1989  (4)
  • chemotherapy  (2)
  • Farnsworth-Mansell 100-hue  (1)
  • Haemolytic uraemic syndrome  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The polymorphonuclear leucocyte count in childhood haemolytic uraemic syndrome (1989)
    Springer
    Pediatric nephrology 3 (1989), S. 130-134 
    Details
    ISSN: 1432-198X
    Keywords: Haemolytic uraemic syndrome ; Polymorphonuclear leucocyte count
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Review of data from 79 children with the haemolytic uraemic syndrome (HUS) showed that the polymorphonuclear leucocyte (PMN) count at presentation in childhood HUS predicts outcome. Logistic regression analysis of several features at presentation identified only the PMN count and the presence of a diarrhoeal prodrome as having a significant effect on the outcome (P〈0.01 andP〈0.001 respectively). The geometric mean PMN count was significantly raised in 70 children who had typical HUS following a diarrhoeal prodrome (D+cases) compared with that of 9 children who had atypical disease without diarrhoea (D-cases) (t-test on log-transformed data,P〈0.005). Fifty-seven children with D+HUS who recovered completely had a significantly lower geometric mean PMN count than D+cases with a bad outcome (P〈0.001). Four of these patients, who died in the acute stage of the disease, had a significantly higher mean count than the rest of the D+patients (P〈0.001). Multiple regression analysis demonstrated that the PMN count in D+cases was not significantly influenced by haemoglobin concentration, platelet count, length of the prodrome, or the administration of antibiotics in the prodromal period. A high PMN count at presentation in D+HUS indicates a poor prognosis. The data emphasise the heterogeneity of HUS and suggest that PMN participate in the pathogenesis of the disorder in typical D + cases but not in atypical D- cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00852893
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Computer analysis of Farnsworth-Munsell 100-hue test (1986)
    Springer
    Documenta ophthalmologica 62 (1986), S. 61-72 
    Details
    ISSN: 1573-2622
    Keywords: Farnsworth-Mansell 100-hue ; computer diagnosis ; computer interpretation ; computer averaging ; axis calculation ; color vision
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Color vision abnormalities indicated by the Farnsworth-Munsell 100-hue Color Vision Tests (FM-100) were analyzed by computer to better characterize and group congenital and acquired color vision disorders and to help establish statistically significant diagnostic criteria. Standard evaluation of the FM-100 is by axis and error score calculations. A method has been established for computer-averaging many tests from patients with the same color abnormalities determined by history, standard FM-100 and Nagel anomaloscope. The computer calculated an average error score and standard deviation for each of the 85 color caps. Every time a new patient was evaluated for color vision abnormality, his score was compared with averaged tests with common diagnoses, by calculating distance scores. The averaged test with the lowest distance score consistently tended to coincide with the diagnosis. An analysis of 130 FM-100 color tests found technician-calculated error scores to be incorrect, although usually minor, in 40% of the tests. The computer-calculated axes agreed well with the technician's estimates. The distance scores predicted the diagnosis accurately 89% of the time. Many errors were due to the small number of protanopes averaged and inability to distinguish trichromats from dichromats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00140548
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Treatment of stage III breast cancer (1989)
    Springer
    Breast cancer research and treatment 13 (1989), S. 225-235 
    Details
    ISSN: 1573-7217
    Keywords: chemotherapy ; combination therapy ; hormonal synchronization ; locally advanced breast cancer ; preoperative chemotherapy ; prognosis ; radiotherapy ; staging, surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A major question in oncology today concerns the most appropriate therapy for locally advanced breast cancer. Realistic goals include effective local treatment and a prolonged disease-free interval for these patients, most of whom have incurable disease. Here, our panel discusses the roles of surgery, radiation therapy, chemotherapy, and hormonal therapy, and the proper sequencing of these modalities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02106572
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Adjuvant therapy in node-negative breast cancer (1989)
    Springer
    Breast cancer research and treatment 13 (1989), S. 97-115 
    Details
    ISSN: 1573-7217
    Keywords: adjuvant therapy ; chemotherapy ; clinical trials ; estrogen receptor ; node-negative breast cancer ; prognostic factors ; tamoxifen ; toxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01806522
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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