ISSN:
1432-1238
Schlagwort(e):
Hemofiltration
;
Flecainide
;
Atrial fibrillation
;
Pharmacokinetics
;
Renal failure
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract Flecainide, a new antiarrhythmic drug, has been shown not no be removed to a significant extent by hemodialysis or peritoneal dialysis, in spite of a high renal clerance. Its systemic and hemofiltrate clearances, measured in a patient under continuous hemofiltration, were 402 and 19.7 ml/min respectively. The clearance ratio of less than 5% makes the contribution of hemofiltration to the elimination of flecainide clinically negligeable.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00717997
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