ISSN:
1432-1459
Keywords:
Mitochondrial myopathy
;
Encephalopathy
;
Lactic acidosis
;
Coenzyme Q10
;
Therapy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes [MELAS] who had normal mitochondrial enzyme activity, high doses of coenzyme Q10 (CoQ) were administered. Clinical improvement with decreased serum lactate and pyruvate levels was observed. Though the mechanism of action of CoQ is not known, a trial is worthwhile in patients with MELAS.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00314013
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