ISSN:
1432-1106
Keywords:
Chick embryo
;
Optic nerve
;
Monensin
;
Axonal transport
;
Membrane glycoproteins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The effects of intraocular injection of monensin, a specific inhibitor of membrane glycoprotein transport within the axon, on the development of the chick embryo optic nerve were examined. A proportion of axons growing from the monensin-injected eye were misrouted into the opposite optic nerve at the chiasm and grew to the retina of the opposite eye. These results suggest that formation of the decussation pattern at the chiasm primarily depends on neurite fasciculation mediated by membrane glycoproteins.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00248912
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