ISSN:
1432-1432
Keywords:
Cyclization
;
Nucleotide analogues
;
Template-directed condensation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Cyclization of activated nucleotide analogues by intramolecular phosphodiester-bond formation is likely to compete very effectively with template-directed condensation except in the cases of ribo- and arabinonucleotides. This could have excluded derivatives of most sugars from growing polyribonucleotide chains and thus reduced chain-termination in prebiotic polynucleotide synthesis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02143509
Permalink