ISSN:
1432-0428
Keywords:
Glucose tolerance
;
streptozotocin
;
diabetes mellitus
;
intestinal glucose absorption
;
hypoglycaemic extract
;
ouabain
;
serum insulin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The efficacy of a hypoglycaemic plant extract, in common use by Kuwaiti diabetic individuals, was evaluated using both streptozotocin-induced diabetic and normal rats. A significant decrease in blood glucose concentration was demonstrated on glucose tolerance tests, as compared to untreated animals. The sum of the fasting, 1 and 2 h blood glucose values, decreased from 18.5±0.72 to 13.6±0.62mmol/l (p 〈 0.001) and from 58.6±2.83 to 44.5±3.12 mmol/l (p 〈0.005) in normal and diabetic animals treated for 1 week, respectively. Treatment with the extract was not found to significantly alter insulin levels or intestinal glucose absorption. The mode of action of the hypoglycaemic preparation remains to be elucidated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00280886
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