ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Topoisomerase I catalyses changes in the topological state of duplex DNA by concerted breakage and reclosure of one strand of the DNA. The temporary nick provides a swivel which allows the linking number to change, while a covalent linkage between the enzyme and the broken strand stores the energy ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/327638a0
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