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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 67 (1985), S. 322-325 
    ISSN: 1432-0533
    Keywords: Prosencephalon cleavage failure ; Fused cerebral hemispheres ; Absent longitudinal fissure ; Holoprosencephaly ; Bovine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Holoprosencephaly, a rare brain malformation previously unreported in the bovine species, was observed in a female Hereford calf. The malformation was characterized by lack of the longitudinal cerebral fissure and the falx cerebri with fusion of the cerebral hemispheres and a single hydrocephalically dilated lateral ventricle, absence of olfactory bulbs and nerves, corpus callosum and septum pellucidum, and heterotopia. The face was flat. There were mild ocular hypotelorism and severe microphthalmia. The morphological features of this bovine case were compared to those of human infants, and various possible etiologic factors and pathogenesis were discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 69 (1986), S. 161-164 
    ISSN: 1432-0533
    Keywords: Canine neuronal ceroidosis ; Blue Heeler dog ; Autofluorescent intraneuronal granules ; Pleomorphic membranogranular cytosomes ; Central nervous system neurons
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neuronal ceroidosis was observed in an 18-month-old male Blue Heeler dog which was euthanized after showing a progressive gait and behavior abnormality, depression, paresthesia, and vision deterioration. The brain was slightly atrophic. Histopathology revealed autofluorescent, periodic acid-Schiff, luxol fast blue, and oil red O-positive intracytoplasmic granules in the neurons of the brain and spinal cord. There was a moderate diffuse reduction in the number of cerebellar and cerebrocortical neurons. Ultrastructurally, these neuronal cytosomes were diverse with preponderance of membranous profiles and granular matrix.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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