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  • 1
    Electronic Resource
    Electronic Resource
    Effective peri-operative pain management in cancer patients (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 44 (1989), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1989.tb09168.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    DNA flow cytometry of thymomas (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 15 (1989), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Forty-seven thymomas have been examined by DNA flow cytometry and results correlated with histology, stage, associated clinical features and survival. Twenty-five cases were DNA diploid, 14 were ancuploid and no results could be obtained for eight cases. The presence of ancuploidy correlated with more advanced (stage II and III) disease and the presence of myasthenia gravis and was more frequent in epithelial predominant thymomas. Tumour recurrence was more frequent in DNA aneuploid tumours, stage II/III disease and epithelial predominant neoplasms. Multifactorial analysis showed that DNA aneuploidy was predictive of tumour recurrence independent of the effects of stage and histology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1989.tb03043.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Hepatic morphology and histochemistry of Wilson's disease presenting as fulminant hepatic failure: a study of 11 cases (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 15 (1989), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Eleven cases of Wilson's disease presenting as fulminant hepatic failure were analysed retrospectively to determine the specificity or otherwise of the histological findings. All cases were cirrhotic, eight with a micronodular pattern. There was marked parenchymal collapse with ductular proliferation and mild inflammation. Other features included cholestasis, hepatocyte necrosis, microvesicular fat and nuclear vacuolation. Orcein staining demonstrated copper-associated protein in the periphery of cirrhotic nodules in all cases and also variably within nodules in eight cases. Copper was demonstrable by the rhodanine method in similar locations but the staining reaction was qualitatively weaker in all cases. Characteristically, there was staining of both parenchymal and mononuclear phagocytic cells. This triad of cirrhosis, strong copper-associated protein deposition and copper positivity was not present in a control group of 20 cases of fulminant hepatic failure of other aetiology and with a similar clinical presentation. It is concluded that in the clinical context of fulminant hepatitis the presence of cirrhosis should raise the suspicion of Wilson's disease and that, with routinely processed and stained tissue, including autopsy tissue, the diagnosis can be made histologically.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1989.tb01590.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Malignant epithelioid haemangioendothelioma of the liver: A clinicopathological and histochemical study of 12 cases (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 15 (1989), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe the clinicopathological findings in 12 cases of hepatic epithelioid haemangioendothelioma in order to identify diagnostic and prognostic features of this unusual vascular neoplasm. Three main tumour patterns were observed histologically: (1) a peripheral pattern with neoplastic cells scattered between fairly normal liver cell plates; (2) a cellular pattern showing a confusing admixture of pleomorphic tumour cells and atrophied hepatocytes set in a small amount of fibrous stroma; and (3) a scarred pattern with sparse tumour cells in a dense fibrous matrix. There were two types of vascular invasion: tuft-like intravascular proliferations of epithelioid cells and fibro-thrombotic venous occlusions. Awareness of these different aspects is important, as they are variably sampled by biopsy needles. The clinical course in this series was less favourable than that previously reported. Eight patients have died, in six instances of liver failure within 4–41 months of diagnosis. Extensive involvement of both lobes of the liver heralds imminent hepatic failure. The slow growth of metastases may justify liver transplantation in order to prolong life.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1989.tb03073.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Cellular schwannoma: a distinct pseudosarcomatous entity (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 11 (1987), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Eighteen cases of cellular schwannoma, a recently delineated benign entity, are described. These tumours present most often in middle-aged adults of either sex and show a predilection for the paravertebral region of the mediastinum and retroperitoneum. More than half the tumours macroscopically arose from a nerve but none was associated with von Recklinghausen's disease. The light microscopic features are remarkably consistent but are not immediately recognizable as neural in type. Means of distinction from a malignant nerve sheath tumour and from a variety of other soft tissue tumours are discussed. Immunohistochemical positivity for S-100 protein has been demonstrated in 17 of the 18 cases. Prolonged follow-up has revealed local recurrence in only one case; none has metastasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1987.tb02606.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Metal composition as a natural marker in anthomyiid flyDelia radicum (L.) (1989)
    Springer
    Journal of chemical ecology 15 (1989), S. 1231-1239 
    Details
    ISSN: 1573-1561
    Keywords: Graphite furnace ; heavy metals ; chemoprints ; Delia radicum ; Diptera ; Anthomyiidae ; surface adsorption ; oxidation states ; metal cations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Graphite furnace and flame atomic absorption spectroscopy were used to make quantitative determinations of a range of metallic cation contents of wet-ashed female individuals ofDelia radicum (L.) from a laboratory culture reared under controlled conditions and freeze-dried upon emergence. Analyses were done for seven elements: Fe, Zn, Cu, Pb, AI, Mg, and K. The quantities of K and Mg present were positively related to the dry weight of individual flies, while the others showed an exponential decrease in concentration with increasing fly weight. This difference is attributed to the different roles of surface adsorption of metals with higher oxidation states and the high absorption efficiencies of those existing as oxidation states 1 and 2. The weight of the insect is therefore a major factor in determining the individual's chemoprint. The implications of this observation for other studies are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01014825
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