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  • 1
    Electronic Resource
    Electronic Resource
    Pick body-like inclusions in the dentate fascia of the hippocampus in Alzheimer's disease (1986)
    Springer
    Acta neuropathologica 71 (1986), S. 38-45 
    Details
    ISSN: 1432-0533
    Keywords: Alzheimer's disease ; Pick bodies ; Neurofibrillary degeneration ; Thioflavine-S ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Pick body-like inclusions are described in the granular neurons of the dentate fascia in Alzheimer's disease. The inclusions are round, argyrophilic and stained by thioflavine-S. Immunocytochemically they contain antigenic determinants of neurofilaments and of Alzheimer neurofibrillary tangles. Ultrastructurally they are composed primarily of 15–18 nm straight filaments similar to the neurofibrillary pathology of progressive supranuclear palsy and Pick's disease. The dentate fascia inclusions, as well as cerebellar plaques but not amyloid angiopathy, are found most frequently in association with severe neurofibrillary degeneration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687960
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Do folliculo-stellate adenomas of the pituitary gland exist or are they intrasellar meningiomas? (1988)
    Springer
    Acta neuropathologica 77 (1988), S. 219-223 
    Details
    ISSN: 1432-0533
    Keywords: Meningioma ; Folliculo-stellate cell ; Pituitary neoplasm ; Electron microscopy ; Immunochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A tumor arising in the pituitary fossa and having some of the histological and ultrastructural features of a recently described tumor, purportedly originating from the folliculo-stellate cells of the anterior pituitary, is presented. The results of our ultrastructural and immunohistochemical studies, however, favored a meningeal origin and suggested that the neoplasm was most likely a secretory meningioma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687435
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Immunoreactive keratin with foreign body reaction in anencephaly (1985)
    Springer
    Acta neuropathologica 67 (1985), S. 326-328 
    Details
    ISSN: 1432-0533
    Keywords: Anencephaly ; Immunoreactive keratinin ; Foreign body inflammation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Keratinous material, in the form of epithelial squames often with foreign body reaction and dense gliosis, was demonstrated in all of ten cases of anencephaly by a sensitive and specific immunohistochemical stain. In some cases keratin was not recognized on routine histological stains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687820
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Diffuse Lewy body disease (1987)
    Springer
    Acta neuropathologica 75 (1987), S. 8-15 
    Details
    ISSN: 1432-0533
    Keywords: Choline acetyltransferase ; Lewy body ; Parkinson's disease ; Somatostatin ; Thioflavine S
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Post-mortem pathological and biochemical studies are reported on six patients with progressive dementia. The characteristic pathological finding was neurofilament-containing cytoplasmic inclusions in cortical and subcortical neurons. The clinical and pathological findings were consistent with so-called diffuse Lewy body disease. The patients had variable changes of the Alzheimer type, with five of six patients displaying “plaques only” Alzheimer's changes. Biochemical studies showed profound decreases in neocortical choline acetyltransferase (ChAT) activities that correlated with marked neuronal loss in the basal nucleus of Meynert. ChAT activities were normal in the hippocampus in three patients who also had no significant Alzheimer type hippocampal changes. All patients had decreased cortical somatostatin-like immunoreactivity. Our observations suggest that dementia in diffuse Lewy body disease bears biochemical similarities to Alzheimer's disease, in that biochemical markers for both intrinsic cortical neurons and ascending cholinergic neurons are affected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00686786
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    Paper (German National Licenses)
    Fulltext
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