ISSN:
1420-9071
Keywords:
Pancreatic elastase II
;
α2-macroglobulin
;
aortic elastin
;
human
;
elastinolysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Human α2-macroglobulin-human pancreatic elastase II binding were investigated using a homologous substrate, human aortic elastin, in order to test the enzymatic activity. We demonstrated that two moles of α2-M are required to inhibit one mole of HPEII when the enzyme is added to a mixture of elastin and α2-M. In addition, when the elastase-α2-M complex is prepared under some circumstances, it exhibits an elastinolytic activity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01941542
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