ISSN:
1573-2622
Keywords:
β-blocker
;
glaucoma
;
Pilogel®
;
intra-ocular pressure
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The interim results of a multicentered clinical trial with the combination therapy Pilogel®/topical β-blocker (twice daily) in patients with primary open angle glaucoma or ocular hypertension are discussed. Six patients were treated with Pilogel® and a topical β-blocker for one month. Four out of six patients responded well to the combination therapy. Most patients experienced some difficulty in applying the gel and their eyelids stuck together on awakening. In two patients a superficial punctate keratitis was observed. We found an average decrease in intra-ocular pressure (IOP) of 22.5% 22.5 hours after Pilogel® administration, but there was some tendency towards higher evening values compared to morning values. In view of the appearance of a corneal haze as described by Johnson et al. during long-term treatment, longer follow-up is necessary.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00153508
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