ISSN:
1365-2761
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
,
Medicine
Notes:
Abstract. Sensitized lymphocytes isolated from the immunized eel, Anguilla japonica, upon interaction with the antigens in vitro, elaborated into the medium a soluble factor which was capable of inhibiting the migration of peritoneal exudate cells harvested from guinea pigs. Production of migration inhibition factor (MIF) was greatest to the specific antigen although there was also some nonspecific release. The elaboration of MIF from the sensitized lymphocytes occurred from the third day after immunization of eels and was detectable until day 106. The inhibitory activity from the blood appeared to persist over a longer period compared to that from the spleen and the anterior kidney. The inhibitory activity, however, was diminished by starvation of the immunized eels.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2761.1989.tb00283.x
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