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  • 1980-1984  (1)
  • 1975-1979  (1)
  • Neuroplasticity  (1)
  • Saure Glykosaminoglykane im Innenohr und anderen Organen  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 214 (1976), S. 149-155 
    ISSN: 1434-4726
    Keywords: Acidic glycosaminoglycans in inner ear and other organs ; Electrophoretic microanalysis ; Saure Glykosaminoglykane im Innenohr und anderen Organen ; Elektrophoretische Mikroanalyse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die quantitative und qualitative Analysen der sauren Glykosaminoglykane in den Grundsubstanzen der lateralen Wand des häutigen Labyrinths, der Nieren, des Gehirns und der Leber von Meerschweinchen wurden mittels der elektrophoretischen Mikroanalysenmethode ausgeführt. Die laterale Wand der Schnecke enthielt die höchste Menge (0,46±0,08% pro Trockengewicht) der sauren Glykosaminoglykane, die aus Chondroitinsulfat-B (75%), Chondroitinsulfat-A (12%) und Hyaluronsäure (13%) bestanden. Jedoch schwankt die Zusammensetzung der Glykosaminoglykane im Innenohr, ebenso wie in den anderen Organen, erheblich. Eine mögliche Bedeutung der Glykosaminoglykane für die Funktion des Hörorgans wurde diskutiert.
    Notes: Summary Acidic glycosaminoglycans in the ground substance of the membranous cochlear lateral wall, kidney, brain and liver of the guinea pigs were quantitatively and qualitatively analyzed, using electrophoretic microanalysis. The lateral wall of the cochlea showed highest content (0.46±0.08%/D.W.) of acidic glycosmainoglycans, which were chondroitin sulfate-B (75%), chondroitin sulfate-A (12%) and hyaluronic acid (13%). However, the pattern of these acidic glycosaminoglycans in the inner ear differed from the other organs. A possible role of acidic glycosaminoglycans in the inner ear was discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 56 (1982), S. 255-264 
    ISSN: 1432-0533
    Keywords: Golgi method ; Purkinje cell ; Dendrite ; Neuroplasticity ; Neuropathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Purkinje cells from five autopsy cases (a premature newborn infant, a GM1-gangliosidosis, an olivo-ponto-cerebellar atrophy, a multisystem atrophy involving the spinal cord and the brain stem, and a woman of 82 years) were studied using the Golgi impregnation technique. The results were the following: (1) the Purkinje cells showed different abnormalities in each case; (2) the dedrite and cell body showed not only involutive/degenerative but also progressive/plastic changes at the same time in some cases; (3) Purkinje cells which appeared normal in routine histological preparations showed, in some cases, abnormalities of the dendrite and cell body; (4) the abnormality common to the five cases was the loss of branchlet-spines and/or spiny branchlets, probably resulting in loss of the granule cell-Purkinje cell connection. It is discussed that the Golgi technique as applied to morbid human material will be an indispensable tool in the future for the analysis of disease processes on cellular and neurobiological bases.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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