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  • 1980-1984  (3)
  • 1975-1979  (5)
  • 1
    Electronic Resource
    Electronic Resource
    INFLUENCES OF COLCHICINE, VINBLASTINE AND CYTOCHALASIN ON THE RELEASE OF 5-HYDROXYTRYPTAMINE FROM RAT BRAIN SYNAPTOSOMES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 30 (1978), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Rat brain synaptosomes preincubated with [3H]5-HT. were further incubated and the release of [3H]5-HT from the preparation was studied. The spontaneous release consisted of an initial rapid phase followed by slower release. Incubation with 60 mM-KCl increased the release while 60 mw-NaCl did not affect it. The effect of KG was abolished when NaCl was omitted from the medium. The potassium-induced release was Ca2+ -dependent while that induced by tyramine (10−5-10−4M) and the spontaneous release did not depend on Ca2+. Vinblastine (10−5–2.5 X 10−4 M) caused an increase in the spontaneous release and an decrease in the potassium-induced release, while it completely inhibited the release by tyramine at 2.5 X 10−4 M. Colchicine (5 X 10−5–10−3M) and cytochalasin D (10−5, 10−4 M) failed to produce any change in the release. Cytochalasin B (10−5, 10−4M) increased the spontaneous release and decreased the potassium-induced release but it did not affect the release by tyramine. Colchicine (10−3 M). vinblastine (10−4 M) and cytochalasin B (10−4 M) did not affect significantly Na+.K+-. Mg2- and Ca2+ -ATPase activities. These results suggest that none of microtubules. microfilaments and contractile protein participates in the mechanism of [3H]5-HT release from synaptosomes, in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1978.tb07049.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Near IR surface brightness of southern galactic plane (1979)
    [s.l.] : Nature Publishing Group
    Nature 279 (1979), S. 510-512 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The instrument we used is similar to that described by Ito et al.2. Incident radiation was focused by a ??-cm, Fl.O silicon lens onto 1 1 PbS detectors, with fields of view of 0.5, 0.8 and 1.7 at 2.4 p?, and 2.0 at 3.4 ??. The whole telescope system was cooled by liquid nitrogen to reduce the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/279510a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    γ-Ray burst observed at balloon altitude (1978)
    [s.l.] : Nature Publishing Group
    Nature 272 (1978), S. 337-338 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two modulation collimators were installed in the balloon gondola so that the fields of view of the collimators were pointed towards the zenith, and the directions of the collimator transmission bands projected on the celestial sphere were perpendicular to each other. Scintillation counters of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/272337a0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Improved treadmill to avoid foot and tail injuries of small animals (1982)
    Springer
    Cellular and molecular life sciences 38 (1982), S. 140-141 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A treadmill was improved so as to eliminate foot and tail injuries in small test-animals. The improvement was inexpensive and easily fabricated by the researchers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01944576
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Immunoprecipitation of 125I-insulin crosslinked receptor (1983)
    Springer
    Diabetologia 24 (1983), S. 387-390 
    Details
    ISSN: 1432-0428
    Keywords: Crosslinking ; disuccinimidyl suberate ; insulin receptor ; anti-receptor antibody ; immunoprecipitation ; type B syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 125I-insulin was covalently crosslinked to its receptor on human placental membrane fractions with disuccinimidyl suberate. The 125I-insulin crosslinked receptor was solubilized with Triton X-100 and used as a probe to determine autoantibodies to the insulin receptor in sera from patients with insulin resistance (type B syndrome). When the solubilized 125I-insulin: receptor complex was incubated with these sera and then with anti-human IgG serum, the complex was precipitated as a function of the amount of anti-receptor serum. Unlabelled insulin at concentrations ⩽10 μg/ml did not affect immunoprecipitation of the complex, suggesting that a subpopulation of anti-receptor antibodies recognizes determinants outside the insulin binding region of the receptor molecule. 125I-insulin: receptor complex was precipitated also by the addition of anti-insulin antibodies. The effect of anti-insulin antibody was eliminated by the addition of excess unlabelled insulin. The immunoprecipitation assay using 125I-insulin crosslinked receptor was sensitive and convenient for detecting anti-receptor antibodies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00251830
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  • 6
    Electronic Resource
    Electronic Resource
    An improved method for estimating the activity of a mouse with the photoswitch (1978)
    Springer
    Cellular and molecular life sciences 34 (1978), S. 671-672 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A new method for estimating the activity of a mouse by means of the photoswitch is contrived. This device can follow the activity with high fidelity and notable sensitivity, as compared with the conventional method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01937026
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  • 7
    Electronic Resource
    Electronic Resource
    Bestimmung der chemischen Potentiale des Systems Polychloroprep-Methyläthylketon mittels Uitrazentrifugemessung (1977)
    Springer
    Colloid & polymer science 255 (1977), S. 728-728 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01550237
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Transmitting boundaries for time-harmonic elastodynamics on infinite domains (1981)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 17 (1981), S. 1697-1716 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A finite element method with transmitting boundary is developed for time-harmonic elastodynamics on infinite domains. Only a finite inner domain needs to be discretized into conventional finite elements, while the effect of the exterior domain is simulated by introducing the transmitting boundary stiffness matrix on the degrees-of-freedom of the transmitting boundary nodes. In order to incorporate the Sommerfeld radiation condition, the reciprocity relation, on the transmitting boundary for the radiating elastodynamic state under consideration and the one which is induced by a finite number of point source is used to calculate the transmitting boundary stiffness matrix. The effectiveness of the transmitting boundary technique has been demonstrated by solving the stress concentration problems of a homogeneous isotropic full space with a circular cylindrical cavity and of the one with a spherical cavity, which are subjected to plane incident waves, and the results are compared with the ones of the conventional FEM and the exact data.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620171109
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