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  • 1980-1984  (1)
  • 1970-1974  (1)
  • Androgen metabolism  (1)
  • Fine structure  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Interaction of prolactin and testosterone in the human prostate (1981)
    Springer
    Urological research 9 (1981), S. 79-88 
    Details
    ISSN: 1434-0879
    Keywords: Prolactin ; Prostate cancer ; Benign prostatic hyperplasia ; Androgen metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three experiments were performed to determine whether human prolactin (hPr) affects prostatic uptake and metabolism of testosterone (T). 1) Patients with prostatic cancer were infused twice with radio-labelled androgens, the first time with basal hPr, the second time with oral thyrotrophin-releasing hormone (TRH)-elevated hPr. In 5/7, significant increases in metabolic clearance of dihydrotestosterone (DHT) and in conversion of T to DHT accompanied increased hPr. 2) The incorporation of labelled T into minced benign prostatic hypertrophy (BPH) tissue from subjects with high (40 ng/ml) hPr was measured and was found to be more than twice the uptake into tissue from those with low hPr (6.5±1.9 ng/ml). 3) Uptake and metabolism in vivo of a bolus of 3H-T by BPH and carcinomatous prostates was measured and was far greater in subjects whose hPr was elevated by chlorpromazine than in untreated controls. It is concluded that prolactin increases prostatic uptake and metabolism of T. It is suggested that the best management of prostatic cancer should include depletion of prolactin as well as androgen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256681
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The anatomy of the median ocellus of Limulus (1971)
    Springer
    Cell & tissue research 118 (1971), S. 297-309 
    Details
    ISSN: 1432-0878
    Keywords: Median ocellus ; Limulus ; Fine structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The median ocellus of Limulus consists of irregular groups of large photoreceptor cells which form a cup-shaped retina around the ocellar lens. Each group is surrounded and penetrated by guanophores and glia. The photoreceptor cells have extensive rhabdomeric regions, both along infoldings of cell membranes and between cells. Five-layered junctions occur between rhabdomeric microvilli. An occasional arhabdomeric (AR) cell is associated with a group of photoreceptors. Fine dendritic branches of the AR cell penetrate the rhabdomeric regions and form five-layered junctions with photoreceptor rhabdomeres. Axons of photoreceptor cells, and of at least some AR cells, gather at the proximal side of the cup to form an optic nerve.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331188
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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