ISSN:
1432-1041
Keywords:
thromboxane synthetase inhibitors
;
Raynaud's syndrome
;
systemic sclerosis
;
UK-38,485
;
ischaemic attacks
;
red blood cell rheology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Ten patients with moderate to severe Raynaud's syndrome were recruited into a four week randomised double blind crossover study to compare the efficacy of UK-38,485 50 mg, a new thromboxane synthetase inhibitor with that of placebo. With the doses used there was no significant difference between the two treatment periods in the number, severity and duration of ischaemic attacks, the mean hand temperatures, forearm and digital blood flow and red blood cell rheology.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00553156
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