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  • 1980-1984  (3)
  • 1935-1939
  • Life and Medical Sciences  (2)
  • Hallux valgus  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 5 (1981), S. 111-115 
    ISSN: 1432-5195
    Keywords: Hallux valgus ; Gait analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs décrivent une méthode d'évaluation globale du pied, tant avant qu'après correction chirurgicale, chez des adolescents porteurs d'hallux valgus. Elle nécessite une série d'études des caractéristiques cliniques, photographiques et radiologiques, ainsi qu'une évaluation dynamique de la marche à l'aide d'un plateau de force. Cette méthode a été utilisée pour estimer avec exactitude les modifications survenues sur 36 pieds après que l'hallux valgus ait été traité par une variante de l'ostéotomie oblique du premier métatarsien décrite par Wilson, qui consiste en une résection d'un coin osseux suivie de fixation par une vis. Durant les six premiers mois post-opératoires, on note un déplacement de l'appui de l'avant-pied vers le dehors et une diminution de la charge au niveau des orteils, mais il y a une tendance à revenir à la répartition pré-opératoire de l'appui au cours des quatre années suivantes. La persistance du déplacement externe de l'appui semble résulter de la surélevation de la tête du premier métatarsien, conséquence du raccourcissement de cet os créé par l'ostéotomie. Ceci peut être évité en abaissant délibérément la première tête métatarsienne lors de l'opération et en fixant les fragments par une vis dans la position désirée.
    Notes: Summary A comprehensive method of evaluating the feet of patients with adolescent hallux valgus both before and after surgical correction is described. Serial clinical, photographic and radiological studies were made and a dynamic assessment of gait was carried out using a load-sensitive walkway. Observations were made on 36 feet in which hallux valgus was treated by a modification of the Wilson oblique metatarsal osteotomy, with removal of a wedge of bone and screw fixation. In the first six months after operation, there was a lateral shift of the weight-bearing pattern in the forefoot and less weight was taken on the toes, but there was a tendency to return to the pre-operative distribution of weight during the next four years. Persistence of the lateral shift of weight-bearing appeared to result from elevation of the first metatarsal head secondary to shortening of the first metatarsal during the osteotomy. This can be avoided by deliberate depression of the first metatarsal head at the time of operation and fixation of the fragments in the required position with a screw.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The introductory review amplifies the finding that simply holding lymphocytes in vitro reversibly compromises their ability to enter lymph nodes from the blood, although entry into the spleen is unaffected. The differential migration of T and B lymphocytes from the blood, lymphocyte traffic in athymic rats, and the secretion of a sulphated glycoconjugate by high endothelial cells in lymph nodes are also discussed.Original data are presented concerning the effects of varying the conditions under which lymphocytes are held in vitro (time, temperature, medium, centrifugation) on their ability to enter lymph nodes and also on their surface morphology. In general, conditions that reduced the number of microvilli and induced surface blebbing also tended to affect the delicate function of crossing specialized vascular endothelium; but there was no simple relationship between morphology and migratory behavior. The localization of lymphocytes to the bone marrow was augmented by holding them in vitro, and this effect was greater after holding at room temperature (RT) than at 0°C, in contrast to impaired entry into lymph nodes. Small amounts of heparin (10 units) injected along with lymphocytes significantly reduced early localization in lymph nodes. These findings have practical implications for the design of lymphocyte traffic experiments and are relevant to the mechanism of lymphocyte attachment to vascular endothelium, since the well-known effect of trypsinizing lymphocytes can be reproduced by maintenance in vitro.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 111 (1982), S. 177-186 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have isolated continuously growing cell lines derived from mouse bone marrow stroma. These cell lines were independently obtained, and though they showed morphologies ranging from the epithelioid to the fibroblastoid patterns, they all differentiated into adipocytes. Subclones obtained from two cell lines had a very high frequency (90-100%) of differentiation into adipocytes after two or three weeks of arrested growth. Though extensive accumulation of lipid often mechanically impaired mitosis, the cells committed to adipocytes did not suffer an irreversible loss of proliferative capacity. Adipogenesis was obtained in conditions similar to those required for fat cell formation in long-term bone marrow culture. The cell lines were found to be insensitive to insulin as a signal of adipocyte differentiation. The ultrastructural characteristics of the preadipocytes and fat cells are also similar to those of the fat cells developing in long-term bone marrow culture. As such, these cell lines should prove useful for analysing cell/cell interactions in haemopoiesis.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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