ISSN:
1432-2072
Keywords:
Amphetamine
;
Saccades
;
Smooth pursuit
;
Psychomotor response
;
Humans
;
Drugs
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Healthy volunteers received single oral or intravenous doses of d-amphetamine sulphate (15 mg) and placebo in a double blind randomized design. Peak velocity of horizontal saccadic eye movements, saccade duration, saccade reaction time and smooth pursuit velocity were measured at intervals up to 1 h (IV) and 6 h (oral) after drug administration. Amphetamine produced no significant effect on saccadic and smooth-pursuit eye movements after oral administration. However, intravenous amphetamine abolished the effect of fatigue on saccadic movements and significantly (P〈0.01) shortened saccadic reaction time.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00427810
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