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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 270 (1981), S. 129-140 
    ISSN: 1432-069X
    Keywords: Aetiology of psoriasis ; Persistence of production of human growth hormone ; Ätiologie der Psoriasis ; Produktionspersistenz des menschlichen Wachstumshormons
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Pathologische Veränderung der Capillaren, gesteigerte Epidermopoese, erhöhter Metabolismus der Psoriasis-Efflorescenz und vorwiegende Manifestation nach dem zweiten Lebensjahrzehnt führten zur Bestimmung des menschlichen Wachstumshormons im Blutserum. Bei 70 Psoriasis-Patienten konnte eine mit der Ausdehnung der Hauterscheinungen, der Akuität und Behandlung signifikant korrelierte Erhöhung des Serumspiegels and Wachstumshormonen gegenüber 40 Kontrollpersonen festgestellt werden. Die ätiologische Bedeutung der hereditären Produktionspersistenz des menschlichen Wachtumshormons wird diskutiert.
    Notes: Summary Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psoriasis we found that the extention of skin lesions was correlated to the STH levels, which were determined every 2 h all over the day. The average STH level in psoriasis was three times as high as average value in the group of 40 controls. Thus, one can conclude that psoriasis is caused by a persistence of STH with individual penetrance.
    Type of Medium: Electronic Resource
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